Retrospective Analysis for Patients With Metabolic Syndrome

NCT06182618 | Unknown

• 1 other identifier: 2023-1042
• Study Type: observational
• Target: 400
• Locations: 1 country
• Sites: 1

Brief Summary

The incidence of metabolic syndrome and related diseases is gradually increasing, and diet and medication are currently common outpatient treatment methods. This study retrospectively analyzes the clinical data of patients with metabolic syndrome and related diseases who have visited our outpatient department in the past 10 years, compares the therapeutic effects of different treatment methods on their blood glucose, blood lipids, blood pressure, uric acid, and body composition, and provides evidence support for clinical treatment.

Conditions

Metabolic Syndrome

Outcome Measures

Primary Outcomes (1)

• weight

  Weight was measured through multi-frequency bioelectrical impedance analysis InBody 720 (Bio Space Co., Seoul, Korea) at various time points

  0month/1month/2months/3 months

Secondary Outcomes (2)

• visceral fat area(VFA)

  0month/1month/2months/3 months

• skeletal muscle mass(SMM)

  0month/1month/2months/3 months

Study Arms (3)

low-carbohydrate diet

20-30% carbohydrates, 40-45%fat, and 30-40%protein

Other: dietary, semaglutide or/and metformin

balanced diet

50-65% carbohydrate, 20-30% fat and 10-20% protein

Other: dietary, semaglutide or/and metformin

pharmacotherapy

semaglutide (1mg per week) or/and metformin (o.5g three times a day)

Other: dietary, semaglutide or/and metformin

Interventions

dietary, semaglutide or/and metformin OTHER

patients were prescribed dietary and pharmaceuticals for weight loss

balanced diet; low-carbohydrate diet; pharmacotherapy

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

This was a retrospective study of the weight loss effect in 1 to 3 months in overweight or obese individuals at the department of clinical nutrition in the Second Affiliated Hospital of Zhejiang University, School of Medicine in China between 1 January 2020 and 1 Janu-ary 2024.

You may qualify if:

• individuals who had at least a 2 follow up visits with a BMI of 24 or more with the pri-mary goal of losing weight.

You may not qualify if:

• patients did not follow-up on a monthly basis;
• patients followed-up less than 1 times within 3 months;
• patients having incomplete data;
• patients changing their interventions during fol-low-ups

Sponsors & Collaborators

• Second Affiliated Hospital, School of Medicine, Zhejiang University: lead

Study Sites (1)

The Second Affiliated Hospital, College of Medicine, Zhejiang University

Hangzhou, Zhejiang, 310009, China

RECRUITING

MeSH Terms

Conditions

Metabolic Syndrome

Interventions

Diet

Condition Hierarchy (Ancestors)

Insulin Resistance; Hyperinsulinism; Glucose Metabolism Disorders; Metabolic Diseases; Nutritional and Metabolic Diseases

Intervention Hierarchy (Ancestors)

Nutritional Physiological Phenomena; Diet, Food, and Nutrition; Physiological Phenomena

Central Study Contacts

leilei wang

CONTACT

0571-87783851; 2513118@zju.edu.cn

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: November 30, 2023
• First Posted: December 27, 2023
• Study Start: June 1, 2023
• Primary Completion: January 1, 2024
• Study Completion: January 1, 2024
• Last Updated: December 27, 2023

Record last verified: 2023-11

Locations

CN (1)