Postoperative Analgesis for Pain Management After Thoracotomy

NCT06177652 | Completed

• 1 other identifier: KAEK/10.bI.02
• Study Type: interventional
• Target: 58
• Locations: 1 country
• Sites: 2

Brief Summary

Thoracotomy is among the most painful surgical procedures and can cause severe pain. Postoperative pain causes many complications. Therefore, pain management is important in patients undergoing thoracotomy. For this purpose, systemic analgesics are used along with ultrasound-guided nerve blocks in thoracotomy pain. The effectiveness of thoracic paravertebral block and serratus plane block in the treatment of post-thoracotomy pain will be evaluated by comparing their effectiveness and complications on postoperative pain. Since the epidural spread of the thoracic paravertebral block is more effective, the effectiveness of postoperative pain relief will be more effective

Conditions

Postoperative Pain; Analgesia

Keywords

Regional Anesthesia; Paravertebral Block; Serratus Plane Block; Thoracotomy

Outcome Measures

Primary Outcomes (1)

• Morphin consumption

  Patient in both groups will provide with intravenous patient-controlled analgesia device containing morphine for postoperative analgesia

  during postoperative 24 hour

Secondary Outcomes (1)

• Visual Analogue Scale (VAS)

  during postoperative 24 hour

Study Arms (2)

Paravertebral Block

ACTIVE COMPARATOR

Ultrasound (US) -guided paravertebral block (PVB) with 20 ml 0.5 % bupivacaine will performe preoperatively to all patients in the PVB group.

Other: Paravertebral Block

Serratus Plane Block

ACTIVE COMPARATOR

Ultrasound (US) -guided serratus plane block (SPB) with 20 ml 0.5 % bupivacaine will performe preoperatively to all patients in the SPB group.

Other: Serratus Plane Block

Interventions

Paravertebral Block OTHER

Ultrasound (US) -guided paravertebral block (PVB) with 20 ml 0.5 % bupivacaine will performe preoperatively to all patients in the PVB group.

Paravertebral Block

Serratus Plane Block OTHER

Ultrasound (US) -guided serratus plane block (SPB) with 20 ml 0.5 % bupivacaine will performe preoperatively to all patients in the SPB group.

Serratus Plane Block

Eligibility Criteria

• Age: 18 Years - 75 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• aged patients
• American Society of Anesthesiologists Classification (ASA) I-II-III patients
• patients who scheduled elective thoracic surgery

You may not qualify if:

• American Society of Anesthesiologists Classification (ASA) IV-V patients
• patients with coagulopathy
• patient with infection at the injection site

Sponsors & Collaborators

• Kocaeli University: lead

Study Sites (2)

Kocaeli University

Kocaeli, Turkey (Türkiye)

Location

Nur Nazire Yucal

Kocaeli, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Pain, Postoperative; Agnosia

Condition Hierarchy (Ancestors)

Postoperative Complications; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Pain; Neurologic Manifestations; Signs and Symptoms; Perceptual Disorders; Neurobehavioral Manifestations; Nervous System Diseases

Study Officials

• Tülay Çardaközü

  Kocaeli University

  STUDY DIRECTOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Masking Details: Single(Participant)
• Purpose: DIAGNOSTIC
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Doctor

Study Record Dates

• First Submitted: December 11, 2023
• First Posted: December 20, 2023
• Study Start: June 1, 2022
• Primary Completion: July 4, 2024
• Study Completion: July 4, 2024
• Last Updated: March 10, 2025

Record last verified: 2025-03

Data Sharing

• IPD Sharing: Will not share

Locations

TU (2)