Study of a Series of Patients Treated for Retrograde Cricopharyngeal Muscle Dysfunction Syndrome

NCT06174831 | Unknown

• 1 other identifier: 8782
• Study Type: observational
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

R-CPD syndrome (Retrograde Cricopharyngeal Dysfunction syndrome) is an inability to burp. It is a syndrome whose diagnosis is clinical, and for which there is effective treatment. Recently treated in the United States (first publication in 2019), this syndrome affects many patients in France and is currently unknown. This study concerns a series of patients treated at the University Hospitals of Strasbourg for a syndrome of retrograde dysfunction of the cricopharyngeus muscle having been treated by injection of botulinum toxin into the cricopharyngeus muscle.

Conditions

Deglutition Disorders

Keywords

Deglutition Disorders; Dysphagia; cricopharyngeus muscle; Circular sphincter; Esophagus; Botulinum toxin

Outcome Measures

Primary Outcomes (1)

• Retrospective description of the characteristics of a series of patients treated for dysphagia syndrome

  Retrospective study of medical files of patients treated in HUS between January 1, 2022 and December 31, 2022

  Through study completion, an average of 2 months

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Major Subject treated by injection of botulinum toxin into the cricopharyngeal muscle after having had a diagnosis of R-CPD in consultation between January 1, 2022 and December 31, 2022

You may qualify if:

• Major subject (≥18 years old)
• Subject treated by injection of botulinum toxin into the cricopharyngeal muscle after having had a diagnosis of R-CPD in consultation between January 1, 2022 and December 31, 2022
• Subject not opposing the reuse of their data for the purposes of this research.

You may not qualify if:

• Subject having expressed opposition to participating in the study,
• Subject under judicial protection
• Subject under guardianship or curatorship

Sponsors & Collaborators

• University Hospital, Strasbourg, France: lead

Study Sites (1)

Service d'ORL et de Chirurgie Cervico-faciale - CHU de Strasbourg - France

Strasbourg, 67091, France

RECRUITING

MeSH Terms

Conditions

Deglutition Disorders

Condition Hierarchy (Ancestors)

Esophageal Diseases; Gastrointestinal Diseases; Digestive System Diseases; Pharyngeal Diseases; Otorhinolaryngologic Diseases

Central Study Contacts

Christian DEBRY, MD, PhD

CONTACT

33 3 88 12 76 44; christian.debry@chru-strasbourg.fr

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: October 23, 2023
• First Posted: December 18, 2023
• Study Start: February 1, 2023
• Primary Completion: January 1, 2024
• Study Completion: January 19, 2024
• Last Updated: December 18, 2023

Record last verified: 2023-10

Locations

FR (1)