Health Systems and Policy Contexts of Medical Oxygen

NCT06169514 | Recruiting

• 1 other identifier: HREC 100143
• Study Type: observational
• Target: 1
• Locations: 6 countries
• Sites: 6

Brief Summary

This is a mixed-methods program evaluation from a health systems and policy perspective, involving (i) stakeholder analysis, (ii) policy-implementation gap analysis, and (iii) comparative country case studies. This study aims to understand how national oxygen strategies achieve impact at national, and subnational level, across country contexts, at what cost. The the investigators seek to:

1. 1.Involve policymakers, implementers (including private sector), and medical oxygen users in identifying challenges and understanding potential solutions to medical oxygen access;
2. 2.Generate new data on how medical oxygen systems work and can be improved from multiple perspectives;
3. 3.Draw lessons on medical oxygen that can directly inform national and global practice and policy.

Conditions

Hypoxemia; Morality; Pneumonia

Keywords

Health system; Oxygen; Oxygen systems; Oxygen access; Pulse oximetry

Outcome Measures

Primary Outcomes (1)

• In-depth stakeholder interviews on national medical oxygen strategies

  In depth stakeholder interviews covering perspectives on policies, oversight, implementation, and related support towards the particular domain (e.g. measurement and indicators, health workforce capacity building, etc.)

  4 years

Study Arms (1)

Policy and stakeholder analysis across 6 countries

Policy and stakeholder analysis across 6 countries

Other: No intervention

Interventions

No intervention OTHER

No intervention

Policy and stakeholder analysis across 6 countries

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

This study will be conducted in 6 of the 9 countries participating in the CHAI-led MOXY program (Uganda, Nigeria, Rwanda, Liberia, Lao PDR, Cambodia).

Key informants will be selected representing government, non-governmental agencies, professional associations, private sector, and civil society.

Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.

Sponsors & Collaborators

• Murdoch Childrens Research Institute: lead
• University of Ibadan: collaborator
• University of Health Sciences, Lao People's Democratic Republic (PDR): collaborator
• University of Health Sciences, Cambodia: collaborator
• Makerere University: collaborator
• Ministry of Health, Liberia: collaborator
• Ministry of Health, Rwanda: collaborator
• Karolinska Institutet: collaborator

Study Sites (6)

Cambodia

Phnom Penh, Cambodia

RECRUITING

Lao PDR

Vientiane, Laos

RECRUITING

Liberia

Monrovia, Liberia

RECRUITING

Nigeria

Ibadan, Nigeria

RECRUITING

Rwanda

Kigali, Rwanda

RECRUITING

Uganda

Kampala, Uganda

RECRUITING

MeSH Terms

Conditions

Hypoxia; Pneumonia

Condition Hierarchy (Ancestors)

Signs and Symptoms, Respiratory; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Respiratory Tract Infections; Infections; Lung Diseases; Respiratory Tract Diseases

Study Officials

• Hamish Graham, PhD

  Murdoch Childrens Research Institute

  PRINCIPAL INVESTIGATOR

• Carina King, PhD

  Karolinska Institutet

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Rami Subhi, MBBS, FRACS, MD (Res)

CONTACT

+61403151186; rami.subhi@mcri.edu.au

Hamish Graham, PhD

CONTACT

+61403456262; hamish.graham@rch.org.au

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: OTHER
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: October 29, 2023
• First Posted: December 13, 2023
• Study Start: July 31, 2024
• Primary Completion (Estimated): December 1, 2027
• Study Completion (Estimated): December 1, 2027
• Last Updated: February 6, 2026

Record last verified: 2025-11

Data Sharing

• IPD Sharing: Will not share

Locations

LI (1); RW (1); CA (1); NG (1); UG (1); LA (1)