Whitening Efficacy and Tooth Sensitivity of Different Concentrations of Hydrogen Peroxide Photoactivated With Violet or Blue LEDs

NCT06165458 | Completed

• 1 other identifier: UFPara017
• Study Type: interventional
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

This is a randomized, controlled, double-blind and repeated-measures clinical trial evaluated the photoactivation of hydrogen peroxide gels in different concentrations with blue or violet LED in terms of whitening efficacy and tooth sensitivity.

Conditions

Color; Bleaching Sensitivity

Outcome Measures

Primary Outcomes (2)

• Color

  A operator measured the color of the six upper anterior teeth using a digital spectrophotometer (VITA Easyshade V, Wilcos, Petrópolis, RJ, Brazil).

  Color assessment was carried out before bleaching, 1 week after bleaching and 3 months after bleaching

• Bleaching Sensitivity

  The degree of tooth sensitivity of patients was recorded using a visual analogue scale (VAS) from 0 to 10, where 0 represents no tooth sensitivity and 10 represents the greatest tooth sensitivity ever felt by the patient.

  Assessments were carried out three times: before bleaching, immediately after bleaching, and 24 hours after bleaching.

Study Arms (4)

HP6V

EXPERIMENTAL

6% hydrogen peroxide gel + violet LED

Other: 6% hydrogen peroxide gel + violet LED

HP6B

EXPERIMENTAL

6% hydrogen peroxide gel + blue LED

Other: 6% hydrogen peroxide gel + blue LED

HP35V

EXPERIMENTAL

35% hydrogen peroxide gel + violet LED

Other: 35% hydrogen peroxide gel + violet LED

HP35B

EXPERIMENTAL

35% hydrogen peroxide gel + blue LED

Other: 35% hydrogen peroxide gel + blue LED

Interventions

6% hydrogen peroxide gel + violet LED OTHER

Tooth whitening with 6% hydrogen peroxide gel (Lase Peroxide Lite, DMC, São Carlos, Brazil) activated by violet LED

HP6V

6% hydrogen peroxide gel + blue LED OTHER

Tooth whitening with 6% hydrogen peroxide gel (Lase Peroxide Lite, DMC, São Carlos, Brazil) activated by blue LED

HP6B

35% hydrogen peroxide gel + violet LED OTHER

Tooth whitening with 35% hydrogen peroxide gel (Lase Peroxide Sensy, DMC, São Carlos, Brazil) activated by violet LED

HP35V

35% hydrogen peroxide gel + blue LED OTHER

Tooth whitening with 35% hydrogen peroxide gel (Lase Peroxide Sensy, DMC, São Carlos, Brazil) activated by blue LED

HP35B

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• at age 18 or older, with good general and oral health;
• possessing all six natural and healthy upper anterior teeth with a color shade of A2 or darker, determined by comparison with the Vita Classic scale;

You may not qualify if:

• pregnant and breastfeeding women;
• individuals with internal tooth discoloration (tetracycline stains, fluorosis or hypoplasias);
• smokers, or those with veneers or restorations on the teeth in questions were excluded;
• gingival recession;
• dentin exposure;
• periodontal disease.

Sponsors & Collaborators

• Universidade Federal do Para: lead

Study Sites (1)

Federal University of Pará

Belém, Pará, 66075-110, Brazil

Location

Related Publications (1)

• Oliveira MGVV, Dutra DJB, Costa JLSG, Besegato JF, Barros APO, Oliveira RR, Araujo PV, Alvim HH. Clinical comparison of whitening efficacy and tooth sensitivity of different concentrations of hydrogen peroxide photoactivated with violet or blue LEDs. Lasers Med Sci. 2024 Jul 26;39(1):195. doi: 10.1007/s10103-024-04144-6.

  PMID: 39060473 DERIVED

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Purpose: OTHER
• Intervention Model: FACTORIAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: clinical professor

Study Record Dates

• First Submitted: December 2, 2023
• First Posted: December 11, 2023
• Study Start: January 12, 2021
• Primary Completion: November 3, 2021
• Study Completion: February 15, 2022
• Last Updated: December 15, 2023

Record last verified: 2023-12

Locations

BR (1)