The Role of Cervical Consistency Index and Uterocervical Angles in Medical Termination

NCT06164067 | Completed

• 1 other identifier: 2011-KAEK-25 2022/04-52
• Study Type: observational
• Target: 136
• Locations: 1 country
• Sites: 1

Brief Summary

The main aim of the investigator study is the success of predictivity cervical consistency index (CCI), anterior uterocervical angle (aUCA) and posterior uterocervical angle (pUCA) in second trimester terminations.

Conditions

Second Trimester Abortion; Uterocervical Angle; Cervical Consistency Index

Keywords

medical termination; uterocervical angle; abortion; second trimester

Outcome Measures

Primary Outcomes (1)

• success of predictivity cervical consistency index, anterior uterocervical angle and posterior uterocervical angle

  cervical consistency index (CCI), an ultrasound measurement that aims to estimate cervical softness by measuring the anteroposterior diameter of the uterine cervix before (AP) (millimeter) and at maximal compression (AP') with the vaginal ultrasound probe and calculating the ratio between the two measurements (AP'/AP × 100). Uterocervical angle (UCA) (degree):Transvaginal sonographic images showing technique of measurement of uterocervical angle. UCA was calculated as angle between two lines. The first line was drawn between internal (I) and external ostium (os) (E). The second line was drawn 3 cm parallel to the lower aspect of anterior inner uterine wall passing through the end of the first line at internal os. (in degrees)

  6 months

Secondary Outcomes (1)

• compare the measured ultrasonographic values

  6 months

Study Arms (2)

Pregnant women who abort within 24 hours

Group 1 treatment was completed in the first 24 hours ( who were completely aborted and removed the fetal material and its attachments )

Other: abortus within 24 hours or 24-48 hours

Pregnant women who abort within 24- 48 hours

Group 2 consisted of patients who needed additional cycles and aborted within 24-48 hours.

Other: abortus within 24 hours or 24-48 hours

Interventions

abortus within 24 hours or 24-48 hours OTHER

second trimester medical termination

Also known as: misoprostol

Pregnant women who abort within 24 hours; Pregnant women who abort within 24- 48 hours

Eligibility Criteria

• Age: 18 Years - 45 Years
• Sex: female
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)
• Sampling Method: Probability Sample

Study Population

white people same demographics no socio- cultural difference

You may qualify if:

• women who had a termination indication in the second trimester and had abortion or abortion in our hospital
• women who have had a miscarriage or abortion with a normal vaginal route or hysterotomy

You may not qualify if:

• multiple pregnancies
• pregnant women with misoprostol-related allergies
• scar pregnancies or heterotopic pregnancies
• patients with a history of previous conization or cervical surgery,
• patients with placental invasion anomaly

Sponsors & Collaborators

• Sanliurfa Mehmet Akif Inan Education and Research Hospital: lead

Study Sites (1)

Nefise Nazlı YENIGUL

Bursa, 16110, Turkey (Türkiye)

Location

MeSH Terms

Interventions

Misoprostol

Intervention Hierarchy (Ancestors)

Prostaglandins E, Synthetic; Prostaglandins, Synthetic; Prostaglandins; Eicosanoids; Fatty Acids, Unsaturated; Fatty Acids; Lipids; Autacoids; Inflammation Mediators; Biological Factors

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 6 Months
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Ph.D. Assistant Professor Department of Obstetrics and Gynecology

Study Record Dates

• First Submitted: April 4, 2023
• First Posted: December 11, 2023
• Study Start: February 15, 2022
• Primary Completion: August 15, 2022
• Study Completion: August 15, 2022
• Last Updated: December 11, 2023

Record last verified: 2023-12

Locations

TU (1)