Description of Compliance With Hydroxychloroquine Treatment in Patients With Systemic Lupus Erythematosus

NCT06161363 | Completed

• 1 other identifier: RC31/23/0473
• Study Type: observational
• Target: 102
• Locations: 1 country
• Sites: 1

Brief Summary

The project focuses on non-compliance in patients with systemic lupus erythematosus taking Plaquenil. More than half of patients with chronic illness are not or only poorly compliant with their treatment and lupus is one of them. The investigators want to use an already validated existing questionnaire in English, the Morisky Medication Adherence Scale 8 (MMAS 8). These results will make it possible, after a multivariate study with reference to the gold standard which is hydroxychloroquinemia, to see which exact questions in the questionnaire can be used in general medicine practices in order to detect less or non-compliant patients as early as possible.

Conditions

Lupus Erythematosus

Outcome Measures

Primary Outcomes (1)

• Non-compliance with hydroxychloroquine treatment

  to describe the non-compliance with hydroxychloroquine treatment with the Morisky Medication Adherence Scale

  Day 0

Study Arms (1)

The Morisky Medication Adherence Scale (MMAS-8)

The Morisky Medication Adherence Scale completed by the patients

Other: The Morisky Medication Adherence Scale

Interventions

The Morisky Medication Adherence Scale OTHER

The Morisky Medication Adherence Scale will be completed bu the patients

The Morisky Medication Adherence Scale (MMAS-8)

Eligibility Criteria

• Age: 18 Years - 75 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patient with systemic lupus erythematosus

You may qualify if:

• Age \>18 years
• Patient with systemic lupus erythematosus
• Treatment with PLAQUENIL for \> 6 months with dosage of hydroxychloroquinemia planned during the consultation.

Sponsors & Collaborators

• University Hospital, Toulouse: lead

Study Sites (1)

Toulouse Hospital

Toulouse, France

Location

Study Design

• Study Type: observational
• Observational Model: ECOLOGIC OR COMMUNITY
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: November 29, 2023
• First Posted: December 7, 2023
• Study Start: November 27, 2023
• Primary Completion: November 16, 2024
• Study Completion: December 16, 2024
• Last Updated: December 31, 2025

Record last verified: 2025-12

Locations

FR (1)