Measuring Electrical Properties of Breast Tissues

NCT06157879 | Completed DMC

• 1 other identifier: HREBA.CC-22-0112
• Study Type: interventional
• Target: 50
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this observational study is to use a low-powered microwave imaging system to provide insight into the correlation of electrical properties of breast tissue at microwave frequencies and breast density obtained from mammograms in healthy women between the ages of 18 and 74. The main questions it aims to answer : • Is there a correlation between the electrical properties of breast tissue and breast density obtained from mammograms? Both breasts of each participant will be scanned by the microwave imaging system six times in total.

Conditions

Healthy; Breast

Keywords

women

Outcome Measures

Primary Outcomes (1)

• Measurement of electrical properties of breast tissue

  The electrical properties will be estimated for each volunteer and an image that maps these properties will be created.

  18 months

Secondary Outcomes (1)

• Correlation between the electrical properties of breast tissue and breast density

  18 months

Study Arms (1)

WVI-MIS-01-2022

EXPERIMENTAL

Healthy volunteers

Device: WVI-MIS-01-2022

Interventions

WVI-MIS-01-2022 DEVICE

Microwave scans

WVI-MIS-01-2022

Eligibility Criteria

• Age: 18 Years - 74 Years
• Sex: female
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Must have had a previous mammogram in the last 2 years

You may not qualify if:

• Participants currently undergoing chemotherapy and/or radiation treatment.
• Participants with breast implants.
• Participants who are breast or breastfeeding.
• Participants with active breast infections.
• Participants with nipple piercings (unless they can be removed prior to scanning).
• Participants with an implanted electronic device.
• Participants with physical limitations that prevent them from placing their breasts in the scanner.

Sponsors & Collaborators

• University of Calgary: lead
• Wave View Imaging: collaborator
• Alberta Innovates Health Solutions: collaborator

Study Sites (1)

University of Calgary

Calgary, Alberta, Canada

Location

Related Publications (2)

• Smith, K., et al. "Microwave Imaging of the Breast: Consistency of Measurements Over Time." IEEE Journal of Electromagnetics, RF and Microwaves in Medicine and Biology, vol. 6, no. 1, 2022, pp. 61-67, https://doi.org/10.1109/JERM.2021.3099014.

  BACKGROUND

• Smith K, Bourqui J, Wang Z, Besler B, Lesiuk M, Roumeliotis M, Quirk S, Grendarova P, Pinilla J, Price S, Docktor B, Fear E. Microwave imaging for monitoring breast cancer treatment: A pilot study. Med Phys. 2023 Nov;50(11):7118-7129. doi: 10.1002/mp.16756. Epub 2023 Oct 6.

  PMID: 37800880 BACKGROUND

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: OTHER
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: November 6, 2023
• First Posted: December 6, 2023
• Study Start: May 27, 2024
• Primary Completion: November 18, 2024
• Study Completion: November 18, 2024
• Last Updated: October 8, 2025

Record last verified: 2025-01

Data Sharing

• IPD Sharing: Will not share

Locations

CA (1)