NCT06153030

Brief Summary

BACKGROUND: Acute right lower quadrant pain is a common symptom in emergency departments. The most common etiology is thought to be acute appendicitis. Other etiologies may be overlooked. Acute right colon diverticulitis is one of them. It is usually seen in male and young patients. It is more common in Asian population and rare in Western countries. Ultrasonography (USG) and computed tomography (CT) are used for radiologic diagnosis. OBJECTIVES: The aim of this study was to investigate the diagnosis, treatment and surgical management of right colon diverticulitis.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
20

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Jan 2018

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2018

Completed
5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2022

Completed
6 months until next milestone

Study Completion

Last participant's last visit for all outcomes

June 15, 2023

Completed
5 months until next milestone

First Submitted

Initial submission to the registry

November 22, 2023

Completed
9 days until next milestone

First Posted

Study publicly available on registry

December 1, 2023

Completed
Last Updated

December 1, 2023

Status Verified

November 1, 2023

Enrollment Period

5 years

First QC Date

November 22, 2023

Last Update Submit

November 22, 2023

Conditions

Diverticulitis, Colonic

Keywords

acute diverticulitisright colonemergencypain

Outcome Measures

Primary Outcomes (1)

  • The need for surgical intervention

    The patients were followed up conservatively if they had their diagnosis in the acute settings.

    time frame is the length of stay usually between 1-14 days

Study Arms (1)

Patient with right colonic diverticulitis

Other: no intervention

Interventions

no interventionOTHER

No intervention

Patient with right colonic diverticulitis

Eligibility Criteria

Age18 Years+
Sexall
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients diagnosed with right colonic diverticulitis between the years of 2018-2022

You may qualify if:

  • Patients diagnosed with right colonic diverticulitis

You may not qualify if:

  • \<18 years of age

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Haydarpasa Numune Training and Research Hospital

Üsküdar, Istanbul, 34668, Turkey (Türkiye)

Location

Related Publications (15)

  • Turner GA, O'Grady MJ, Purcell RV, Frizelle FA. The Epidemiology and Etiology of Right-Sided Colonic Diverticulosis: A Review. Ann Coloproctol. 2021 Aug;37(4):196-203. doi: 10.3393/ac.2021.00192.0027. Epub 2021 Jul 21.

    PMID: 34284562BACKGROUND

  • Papatriantafyllou A, Dedopoulou P, Soukouli K, Karioris I, Tsochatzis S. Right-Sided Diverticulitis: A Rare Cause of Right-Sided Abdominal Pain. Cureus. 2023 Apr 4;15(4):e37123. doi: 10.7759/cureus.37123. eCollection 2023 Apr.

    PMID: 37153306BACKGROUND

  • Ma Z, Liu W, Zhou J, Yao L, Xie W, Su M, Yang J, Shao J, Chen J. Management and long-term outcomes of acute right colonic diverticulitis and risk factors of recurrence. BMC Surg. 2022 Apr 7;22(1):132. doi: 10.1186/s12893-022-01578-z.

    PMID: 35392887BACKGROUND

  • Kahveci S, Tokmak TT, Yildirim A, Mavili E. Acute right-sided colonic diverticulitis mimicking appendicitis: a report of two cases. J Clin Ultrasound. 2013 May;41(4):238-41. doi: 10.1002/jcu.21967. Epub 2012 Aug 1.

    PMID: 22855407BACKGROUND

  • Shin JH, Son BH, Kim H. Clinically distinguishing between appendicitis and right-sided colonic diverticulitis at initial presentation. Yonsei Med J. 2007 Jun 30;48(3):511-6. doi: 10.3349/ymj.2007.48.3.511.

    PMID: 17594161BACKGROUND

  • Lee JH, Ahn BK, Lee KH. Conservative treatment of uncomplicated right-sided diverticulitis: a systematic review and meta-analysis. Int J Colorectal Dis. 2021 Aug;36(8):1791-1799. doi: 10.1007/s00384-021-03913-x. Epub 2021 Mar 25.

    PMID: 33765173BACKGROUND

  • Park SM, Kwon TS, Kim DJ, Lee YS, Cheung DY, Oh ST, Kim JG, Lee IK. Prediction and management of recurrent right colon diverticulitis. Int J Colorectal Dis. 2014 Nov;29(11):1355-60. doi: 10.1007/s00384-014-1938-3. Epub 2014 Jul 6.

    PMID: 24997717BACKGROUND

  • Park HC, Kim BS, Lee K, Kim MJ, Lee BH. Risk factors for recurrence of right colonic uncomplicated diverticulitis after first attack. Int J Colorectal Dis. 2014 Oct;29(10):1217-22. doi: 10.1007/s00384-014-1941-8. Epub 2014 Jul 1.

    PMID: 24980689BACKGROUND

  • Kim YC, Chung JW, Baek JH, Lee WS, Kim D, Park YH, Yang JY, Lee WK. Risk Factors for Recurrence of Right Colonic Diverticulitis. Dig Surg. 2019;36(6):509-513. doi: 10.1159/000494297. Epub 2018 Nov 8.

    PMID: 30408791BACKGROUND

  • Kim MR, Kye BH, Kim HJ, Cho HM, Oh ST, Kim JG. Treatment of right colonic diverticulitis: the role of nonoperative treatment. J Korean Soc Coloproctol. 2010 Dec;26(6):402-6. doi: 10.3393/jksc.2010.26.6.402. Epub 2010 Dec 31.

    PMID: 21221240BACKGROUND

  • Lee KY, Lee J, Park YY, Oh ST. Routine colonoscopy may be needed for uncomplicated acute right colonic diverticulitis. BMC Gastroenterol. 2021 Feb 27;21(1):91. doi: 10.1186/s12876-021-01672-1.

    PMID: 33639847BACKGROUND

  • Huang SS, Sung CW, Wang HP, Lien WC. The outcomes of right-sided and left-sided colonic diverticulitis following non-operative management: a systematic review and meta-analysis. World J Emerg Surg. 2022 Nov 1;17(1):56. doi: 10.1186/s13017-022-00463-7.

    PMID: 36320045RESULT

  • Palacios Huatuco RM, Pantoja Pachajoa DA, Liano JE, Picon Molina HA, Palencia R, Doniquian AM, Parodi M. Right-sided acute diverticulitis in the West: experience at a university hospital in Argentina. Ann Coloproctol. 2023 Apr;39(2):123-130. doi: 10.3393/ac.2021.00402.0057. Epub 2021 Nov 24.

    PMID: 34814235RESULT

  • Oh MY, Shin R, Heo SC, Lim HK, Kim MJ, Park JW, Ryoo SB, Jeong SY, Park KJ. Investigation of the clinical features and recurrence patterns of acute right-sided colonic diverticulitis: A retrospective cohort study. Ann Med Surg (Lond). 2022 Aug 18;81:104431. doi: 10.1016/j.amsu.2022.104431. eCollection 2022 Sep.

    PMID: 36147058RESULT

  • Rov A, Ben-Ari A, Barlev E, Pelcman D, Susmalian S, Paran H. Right-sided diverticulitis in a Western population. Int J Colorectal Dis. 2022 Jun;37(6):1251-1256. doi: 10.1007/s00384-022-04135-5. Epub 2022 May 4.

    PMID: 35505198RESULT

MeSH Terms

Conditions

Diverticulitis, ColonicEmergenciesPain

Condition Hierarchy (Ancestors)

DiverticulitisDiverticular DiseasesGastroenteritisGastrointestinal DiseasesDigestive System DiseasesDiverticulosis, ColonicColonic DiseasesIntestinal DiseasesDisease AttributesPathologic ProcessesPathological Conditions, Signs and SymptomsNeurologic ManifestationsSigns and Symptoms

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
CROSS SECTIONAL
Target Duration
1 Year
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Resident Medical Doctor

Study Record Dates

First Submitted

November 22, 2023

First Posted

December 1, 2023

Study Start

January 1, 2018

Primary Completion

December 31, 2022

Study Completion

June 15, 2023

Last Updated

December 1, 2023

Record last verified: 2023-11

Data Sharing

IPD Sharing
Will not share

Locations

TU(1)