Factors Associated With the Acne Severity Among Transmen Population: a Cross-sectional Study

NCT06149065 | Completed

• 1 other identifier: 2124
• Study Type: observational
• Target: 247
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this observational cross-sectional study is to identify factors associated with severity of acne in Thai transmen receiving masculinizing hormone therapy. The main questions it aims to answer are:

• What are the factors associated with severity of acne in transmen?
• Does masculinizing hormone therapy associate with the severity of acne in transmen? Participants will be asked to complete an online questionnaire and allow to take pictures of their face for acne assessment purpose.

Conditions

Acne; Transgenderism

Keywords

Diet, Female-to-male transgender, Masculinizing hormone therapy, Risk factors

Outcome Measures

Primary Outcomes (1)

• The severity of acne

  Investigator Global Assessment (IGA) scale for acne

  1 day (At the time of answering an online questionnaire)

Interventions

Testosterone DRUG

Masculinizing hormone therapy (testosterone) is used in female-to-male transgenders for medical reason.

Also known as: Demographic data, acne-related clinical risk factors

Eligibility Criteria

• Age: 18 Years+
• Gender Eligibility Details: Transgender male (also: trans man, female-to-male, transgender male): this refers to individuals assigned female at birth but who identify and live as men.
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

All transmen who visited the Gender Variation (GenV) Clinic (outpatient clinic) of Ramathibodi Hospital

You may qualify if:

• Transmen who visited the Gender Variation (GenV) Clinic of Ramathibodi Hospital
• Transmen who received masculinizing hormone therapy (testosterone)
• Transmen who completed an online questionnaire and intentional submit their facial photographs

You may not qualify if:

• Refusal to participate
• Incomplete questionnaire
• Missing photos
• Diagnosis of any disorders of sexual differentiation which may have peculiar hormonal effect

Sponsors & Collaborators

• Mahidol University: lead

Study Sites (1)

Division of Dermatology, Department of Internal Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University

Ratchathewi, Bangkok, 10400, Thailand

Location

MeSH Terms

Conditions

Acne Vulgaris; Transsexualism

Interventions

Testosterone; Demography

Condition Hierarchy (Ancestors)

Acneiform Eruptions; Skin Diseases; Skin and Connective Tissue Diseases; Sebaceous Gland Diseases; Sexuality; Sexual Behavior; Behavior

Intervention Hierarchy (Ancestors)

Androstenols; Androstenes; Androstanes; Steroids; Fused-Ring Compounds; Polycyclic Compounds; Testosterone Congeners; Gonadal Steroid Hormones; Gonadal Hormones; Hormones; Hormones, Hormone Substitutes, and Hormone Antagonists; Population Characteristics; Epidemiologic Measurements; Public Health; Environment and Public Health

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: CROSS SECTIONAL
• Target Duration: 17 Months
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: November 20, 2023
• First Posted: November 28, 2023
• Study Start: June 5, 2021
• Primary Completion: June 6, 2023
• Study Completion: June 6, 2023
• Last Updated: November 28, 2023

Record last verified: 2023-11

Locations

TH (1)