NCT06148753

Brief Summary

This is a virtual, single-group clinical trial that will last 8 weeks. Participants will use the Manuka Health Eternal Renewal Regenerating Face Serum with Royal Jelly and Bee Venom twice daily and complete questionnaires at Baseline, Week 2, Week 4, and Week 8. Participants will also undergo skin analysis via the Optic Elite facial skin analysis system at Baseline and Week 8.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
40

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Nov 2023

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 9, 2023

Completed
10 days until next milestone

First Submitted

Initial submission to the registry

November 19, 2023

Completed
9 days until next milestone

First Posted

Study publicly available on registry

November 28, 2023

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 28, 2024

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 28, 2024

Completed
Last Updated

November 20, 2024

Status Verified

November 1, 2024

Enrollment Period

6 months

First QC Date

November 19, 2023

Last Update Submit

November 18, 2024

Conditions

Skin Health

Outcome Measures

Primary Outcomes (1)

  • Changes in signs of skin health over time assessed via Optic Elite Skin Analysis. [Timeframe: Baseline to Week 8]

    The Optic Elite skin analysis system clinically measures the surface and subsurface layers of skin using digital imaging technology

    8 weeks

Secondary Outcomes (8)

  • Changes in self-perceived appearance of fine lines and wrinkles. [Timeframe: Baseline to Week 8]

    8 weeks

  • Changes in self-perceived skin clarity. [Timeframe: Baseline to Week 8]

    8 weeks

  • Changes in self-perceived skin hydration. [Timeframe: Baseline to Week 8]

    8 weeks

  • Changes in self-perceived skin texture. [Timeframe: Baseline to Week 8]

    8 weeks

  • Changes in self-perceived skin hyperpigmentation. [Timeframe: Baseline to Week 8]

    8 weeks

  • +3 more secondary outcomes

Study Arms (1)

Eternal Renewal Regenerating Face Serum

EXPERIMENTAL

Participants will be required to apply the test product in the morning and before sleeping at night. After thoroughly cleansing and toning the face, the participants will apply 2-3 drops onto clean dry fingers and massage over the entire face until fully absorbed. The product should be followed with the participants' preferred moisturizer.

Other: Manuka Health Eternal Renewal Regenerating Face Serum with Royal Jelly and Bee Venom

Interventions

Manuka Health Eternal Renewal Regenerating Face Serum with Royal Jelly and Bee VenomOTHER

Face serum containing manuka honey, royal bee jelly, and bee venom.

Eternal Renewal Regenerating Face Serum

Eligibility Criteria

Age40 Years - 55 Years
Sexfemale
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Female.
  • years of age.
  • Must be in good general health.
  • Must have concerns with overall skin health and appearance, including:
  • Fine lines and wrinkles The appearance of dark spots
  • Must be using the same cleanser, toner, and moisturizer for at least one month prior to starting the study.
  • Must be willing to keep using the same cleanser, toner, and moisturizer for the duration of the study.
  • Must not be using oral or topical retinoids.
  • In the last three months, has not introduced any new medications or supplements that target skin health.
  • Must be willing to comply with the protocol.

You may not qualify if:

  • Anyone with an allergy to bees or bee products.
  • Females who are pregnant or breastfeeding.
  • Unwilling to follow the protocol.
  • Unwilling to maintain use of the same cleaner, toner, and moisturizer for the duration of the study.
  • Currently participating in another study.
  • Use of oral or topical retinoids.
  • Individuals with cystic acne or otherwise self-reported very acne-prone skin.
  • Use of a prescription medication relevant to the skin.
  • Anyone undergoing cosmetic procedures during the study, including Botox, laser, or chemical peel treatments.
  • Anyone sensitive or allergic to any ingredients found in the products.
  • Anyone with severe chronic conditions, including oncological conditions, psychiatric disorders, or diabetes.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Citruslabs

Santa Monica, California, 90404, United States

Location

MeSH Terms

Interventions

royal jellyBee Venoms

Intervention Hierarchy (Ancestors)

Arthropod VenomsVenomsComplex MixturesToxins, BiologicalBiological Factors

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
OTHER
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

November 19, 2023

First Posted

November 28, 2023

Study Start

November 9, 2023

Primary Completion

April 28, 2024

Study Completion

April 28, 2024

Last Updated

November 20, 2024

Record last verified: 2024-11

Locations

US(1)