Exploring the Relationship Between ICOPE Framework and Frailty Among Community-dwelling Elderly Individuals

NCT06140212 | Completed

• 1 other identifier: 202310067RINC
• Study Type: observational
• Target: 135
• Locations: 1 country
• Sites: 1

Brief Summary

This study aims to (1) compare the assessment outcome of the ICOPE-I and ICOPE-S, and (2) investigate the correlation between both versions of the ICOPE step 1 screening tools and frailty in Taiwan.

Conditions

Community-dwelling Elderly

Keywords

Frailty; ICOPE; Intrinsic capacity; Community-dwelling elderly

Outcome Measures

Primary Outcomes (3)

• Intrinsic capacity

  ICOPE screening tool (self-administration and interview version) would be used to evaluate the intrinsic capacity(IC), including cognitive decline, auditory and visual capabilities, mobility restrictions, nutritional status, and depressive symptoms) of the participants. Each question requires a binary response, either 'yes' or 'no'. A "total score" will be determined by summing the number of IC impairments, which have a score range of 0-6, with higher scores indicating a greater degree of impairment.

  The ICOPE screening tool assessment would take about 10 minutes

• Phenotype of frailty status

  Frailty criteria by Dr. Fried would be used to evaluate the frail status of the participants.The Dr. Fried phenotype of frailty comprises five components, unintentional weight loss, exhaustion, weakness, slowness, and low activity. Individuals who exhibit three or more indicators are classified as frail, those with one to two indicators are categorized as pre-frail, and those with no indicators are characterized as robust.

  The phenotype of frailty status assessment would take about 10 minutes

• Accumulated frailty status

  Edmonton frail scale(EFS) would be used to evaluate the frail status of the participants. EFS assesses a wide range of nine domains through 11 questions. These domains cover cognition, general health status, functional independence, social support, medication use, nutrition, mood, continence, and functional performance. The total score of EFS ranges from 0 to 17, where scores of 0-5 indicate not being frail, 6-7 indicate being vulnerable, 8-9 indicate mild frailty, 10-11 indicate moderate frailty and 12-17 indicate severe frailty.

  The accumulated frailty status assessment would take about 10 minutes

Secondary Outcomes (1)

• Cognitive status

  The cognitive status assessment would take about 10 minutes

Study Arms (2)

Decline ICOPE group

The elderly individuals who have at least one impairment in ICOPE screening domains.

Behavioral: Montreal Cognitive Assessment (MoCA); Behavioral: Chinese ICOPE screening tool (self-administration and interview versions); Behavioral: Frailty status assessment (Edmonton frail scale and Frailty criteria by Dr. Fried)

Non-decline ICOPE group

The elderly individuals who do not have any impairment in ICOPE screening domains.

Behavioral: Montreal Cognitive Assessment (MoCA); Behavioral: Chinese ICOPE screening tool (self-administration and interview versions); Behavioral: Frailty status assessment (Edmonton frail scale and Frailty criteria by Dr. Fried)

Interventions

Montreal Cognitive Assessment (MoCA) BEHAVIORAL

MoCA would be used to assess participants cognitive functioning.

Decline ICOPE group; Non-decline ICOPE group

Chinese ICOPE screening tool (self-administration and interview versions) BEHAVIORAL

The ICOPE screening tool would be used to assess participants health status, including cognitive decline, auditory and visual capabilities, mobility restrictions, nutritional status, and depressive symptoms.

Decline ICOPE group; Non-decline ICOPE group

Frailty status assessment (Edmonton frail scale and Frailty criteria by Dr. Fried) BEHAVIORAL

The Edmonton frail scale and Frailty criteria by Dr. Fried would be used to assess participants frailty status.

Decline ICOPE group; Non-decline ICOPE group

Eligibility Criteria

• Age: 65 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Communities in Taipei city

You may qualify if:

• ≥ 65 years old
• Community-dwelling elderly
• Walking independently (with/without assistive devices)

You may not qualify if:

• Participants with a MoCA score \< 26
• Being unable to give informed consent (e.g., aphasia, deafness, and blindness)
• Being unable to finish all the physical and screening assessment assessments

Sponsors & Collaborators

• National Taiwan University Hospital: lead

Study Sites (1)

School and Graduate Institute of Physical Therapy, College of Medicine, National Taiwan University

Taipei, Zhongzheng, 100, Taiwan

Location

MeSH Terms

Conditions

Frailty

Interventions

Mental Status and Dementia Tests; Self Administration

Condition Hierarchy (Ancestors)

Pathologic Processes; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Neuropsychological Tests; Psychological Tests; Behavioral Disciplines and Activities; Drug Therapy; Therapeutics; Self Care

Study Officials

• Li-Ying Wang, PhD

  National Taiwan University

  STUDY CHAIR

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: November 9, 2023
• First Posted: November 18, 2023
• Study Start: December 2, 2023
• Primary Completion: June 25, 2024
• Study Completion: June 25, 2024
• Last Updated: August 12, 2024

Record last verified: 2023-11

Locations

TW (1)