Oxygen Delivery Methods of Nasal Catheter on the Incidence of Hypoxemia in Patients with Painless Gastroscopy

NCT06139081 | Completed

• 1 other identifier: KY20230915-10
• Study Type: interventional
• Target: 648
• Locations: 1 country
• Sites: 1

Brief Summary

In this study, patients undergoing painless gastroscopy were selected to change the nasal catheter oxygen delivery mode to oral oxygen delivery after endoscope implantation, in order to explore the effect of this oxygen delivery mode on the incidence of hypoxemia during general anesthesia gastroscopy.

Conditions

Hypoxemia

Outcome Measures

Primary Outcomes (1)

• Incidence of hypoxemia

  SpO2\<92%

  Five minutes after finishing gastroscopy examination

Study Arms (2)

Group A

EXPERIMENTAL

Transnasal oxygen was administered by nasal catheter before gastroscopy, transoral oxygen was administered by nasal catheter during gastroscopy, and transnasal oxygen was administered by nasal catheter after withdrawal of gastroscope.

Other: Oxygen delivery mode

Group B

NO INTERVENTION

Nasal catheter was used to give oxygen before, during and after withdrawal of gastroscope

Interventions

Oxygen delivery mode OTHER

After the implantation of the mirror, nasal catheter was used to give oxygen through the mouth

Group A

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Patients who receiving gastroscopy under general anesthesia, accompanied with one of the following risk factors of hypoxia:
• Patients combined with heart or respiratory diseases
• Age older than 60
• ASA grading II-III
• BMI≥30kg/m²,
• Snoring or having sleep apnea syndrome
• Patients with a STOP-Bang score ≥ 3 (the risk of OSAS is high) are considered to be highly risk of hypoxia.

You may not qualify if:

• Severe cardiovascular, pulmonary, liver, or kidney disease
• Patients with infections or tumors of airway
• History of difficult intubation under general anesthesia
• Severe sleep apnea syndrome \[hypopnea/apnea hypopnea index (AHI)\>40\]
• Patients allergic to propofol, eggs, soy or egg whites
• Pregnancy

Sponsors & Collaborators

• Nanjing First Hospital, Nanjing Medical University: lead

Study Sites (1)

Nanjing First Hospital

Nanjing, Jiangsu, 210006, China

Location

Related Publications (3)

• Tas Z, Hosten T, Kus A, Cesur S, Turkyilmaz N, Arikan A, Solak ZM. Comparison of tidal volume and deep breath preoxygenation techniquesundergoing coronary artery bypass graft surgery: effects of hemodynamicresponse and arterial oxygenation. Turk J Med Sci. 2017 Nov 13;47(5):1576-1582. doi: 10.3906/sag-1606-132.

  PMID: 29151335 BACKGROUND

• Chen DX, Yang H, Wu XP, Niu W, Ding L, Zeng HL, Li Q. Comparison of a Nasal Mask and Traditional Nasal Cannula During Intravenous Anesthesia for Gastroscopy Procedures: A Randomized Controlled Trial. Anesth Analg. 2022 Mar 1;134(3):615-623. doi: 10.1213/ANE.0000000000005828.

  PMID: 34878412 BACKGROUND

• Gavrilovska-Brzanov A, Shosholcheva M, Kartalov A, Jovanovski-Srceva M, Brzanov N, Kuzamanovska B. Medium-Flow Oxygenation Through Facial Mask and Nasal Cannula in a Limited Resource Setting. Pril (Makedon Akad Nauk Umet Odd Med Nauki). 2022 Jul 13;43(2):101-109. doi: 10.2478/prilozi-2022-0023.

  PMID: 35843919 BACKGROUND

MeSH Terms

Conditions

Hypoxia

Condition Hierarchy (Ancestors)

Signs and Symptoms, Respiratory; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Officials

• Gu Jianping

  Nanjing First Hospital, Nanjing Medical University

  STUDY CHAIR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: October 26, 2023
• First Posted: November 18, 2023
• Study Start: September 22, 2023
• Primary Completion: December 13, 2024
• Study Completion: December 14, 2024
• Last Updated: January 14, 2025

Record last verified: 2024-11

Data Sharing

• IPD Sharing: Will not share

Locations

CN (1)