Intradialytic Aerobic Exercise in CKD Patient

NCT06137937 | Completed

• 1 other identifier: IKFR.10.23
• Study Type: interventional
• Target: 34
• Locations: 1 country
• Sites: 1

Brief Summary

Intradialytic aerobic exercise is not effective in increasing hemodialysis adequacy but is effective in improving physical performance in twice-weekly hemodialysis patients.

Conditions

Chronic Kidney Diseases

Keywords

chronic kidney disease; intradialytic aerobic exercise; physical performance

Outcome Measures

Primary Outcomes (1)

• Kt/V

  Dialysis adequacy (Kt/V) and physical performance test with a Short Physical Performance Battery (SPPB) were evaluated before and after the intervention

  eight weeks

Study Arms (2)

Interventional Group

EXPERIMENTAL

subjects in the treatment group underwent routine hemodialysis by committing to an intradialysis aerobic exercise program

Behavioral: Aerobic Exercise

Control Group

NO INTERVENTION

subjects in the control group underwent routine hemodialysis without a physical exercise program

Interventions

Aerobic Exercise BEHAVIORAL

Intradialytic aerobic exercise for eight weeks

Interventional Group

Eligibility Criteria

• Age: 25 Years - 54 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• End Stage Renal Disease Patient stage 5 with Glomerular Filtration Rate \<15mL/minute/1.73m2 aged 25-54 years undergoing hemodialysis two times per week for three months to five years
• Hemoglobin levels \> 8mg/dl
• Mini-Mental State Examination (MMSE) score of ≥24
• Hamilton Depression Rating Scale (HDRS) score \<25

You may not qualify if:

• Received aerobic exercise in the last 3 months
• History of hospitalization in the last 3 months
• Access for hemodialysis circulation via the femoral vein.
• IMT \<18,5 (underweight) dan ≥35 (obese class II)
• Non-stable cardiovascular disease, uncontrolled glucose, acute infection disease

Sponsors & Collaborators

• Universitas Padjadjaran: lead

Study Sites (1)

Al Ihsan Hospital

Bandung, West Java, Indonesia

Location

Related Publications (2)

• Rhee SY, Song JK, Hong SC, Choi JW, Jeon HJ, Shin DH, Ji EH, Choi EH, Lee J, Kim A, Choi SW, Oh J. Intradialytic exercise improves physical function and reduces intradialytic hypotension and depression in hemodialysis patients. Korean J Intern Med. 2019 May;34(3):588-598. doi: 10.3904/kjim.2017.020. Epub 2017 Aug 25.

  PMID: 28838226 BACKGROUND

• Yabe H, Kono K, Yamaguchi T, Ishikawa Y, Yamaguchi Y, Azekura H. Effects of intradialytic exercise for advanced-age patients undergoing hemodialysis: A randomized controlled trial. PLoS One. 2021 Oct 22;16(10):e0257918. doi: 10.1371/journal.pone.0257918. eCollection 2021.

  PMID: 34679101 BACKGROUND

MeSH Terms

Conditions

Renal Insufficiency, Chronic

Interventions

Exercise

Condition Hierarchy (Ancestors)

Renal Insufficiency; Kidney Diseases; Urologic Diseases; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Male Urogenital Diseases; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Officials

• Irma Ruslina Defi

  Universitas Padjadjaran

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Masking Details: The sample in this study was determined randomly using a computer; subjects in the treatment group underwent routine hemodialysis by committing to an intradialysis aerobic exercise program
• Purpose: SUPPORTIVE CARE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Model Details: Thirty-four participants receiving hemodialysis were randomized to the intervention and control groups.

Study Record Dates

• First Submitted: November 13, 2023
• First Posted: November 18, 2023
• Study Start: November 1, 2023
• Primary Completion: December 27, 2023
• Study Completion: December 27, 2023
• Last Updated: March 24, 2025

Record last verified: 2025-03

Locations

ID (1)