NCT06133868

Brief Summary

The Efficacy of Lavender and Chamomile Essential Oils Inhalation in Management of Dental Anxiety in Children Undergoing Local Anesthesia Administration and Primary Tooth Extraction.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
60

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Dec 2023

Shorter than P25 for not_applicable

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

November 9, 2023

Completed
9 days until next milestone

First Posted

Study publicly available on registry

November 18, 2023

Completed
13 days until next milestone

Study Start

First participant enrolled

December 1, 2023

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2024

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2024

Completed
Last Updated

November 18, 2023

Status Verified

November 1, 2023

Enrollment Period

6 months

First QC Date

November 9, 2023

Last Update Submit

November 14, 2023

Conditions

Outcome Measures

Primary Outcomes (2)

  • Anxiety

    Facial Image Scale (FIS) Score from (1-5) high score means worse outcome Score from (1-5) counting from left to right from 1 = not nervous at all to 5 = very very nervous

    immediately after the intervention

  • pain

    Faces, legs ,activity ,cry , and consolability Score (0-10) high score means worse outcome

    immediately after the intervention

Secondary Outcomes (3)

  • Blood pressure (BP)

    immediately after the intervention

  • Pulse rate

    immediately after the intervention

  • 3. Oxygen saturation

    immediately after the intervention

Study Arms (3)

Group I (Experimental group) Chamomile

ACTIVE COMPARATOR

\- · Describing the method for the child to become familiar with · The patient will inhale natural chamomile oil in a separate room prior to the intervention. Three drops (0.1 cc per drop) will be poured on a cotton roll, and patients will inhale the oil without skin contact for 3 min.

Drug: Lavender and Chamomile Essential Oils

- Group II (Experimental group) Lavender

ACTIVE COMPARATOR

* Describing the method for the child to become familiar with. * The patient will inhale natural lavender oil (100% pure Lavandula) in a separate room prior to the intervention. Three drops (0.1 cc per drop) of lavender oil will be poured on a cotton roll, and patients will inhale the oil without skin contact for 3 min

Drug: Lavender and Chamomile Essential Oils

- Group III (Control group) Cotton with saline

PLACEBO COMPARATOR

* Describing the method for the child to become familiar with * The patient will inhale a clear cotton roll with saline.

Drug: Lavender and Chamomile Essential Oils

Interventions

essential oils

- Group II (Experimental group) Lavender- Group III (Control group) Cotton with salineGroup I (Experimental group) Chamomile

Eligibility Criteria

Age6 Years - 12 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17)

You may qualify if:

  • Patients with primary a mandibular molar that needs to be extracted.
  • Patients aged between 6 and 12 years.
  • Patients in their first dental visit.
  • Patients who are intellectually sufficient to complete the anxiety scale.
  • Children category 2, 3, 4 according to the Frankl Behaviour Rating Scale.
  • Patients whose parents were willing to participate in the study.

You may not qualify if:

  • Patients with common allergies; Paediatric dental local anaesthesia allergies should be excluded to prevent bad reactions. Dental professionals should know how to treat local anaesthetic side effects such allergic and toxic responses. Consider the patient's medical history and physical condition before choosing a local anaesthetic dose and type. Identifying latex allergy patients and avoiding latex-containing products during dental operations is also important. For paediatric dental operations to be safe and effective, individuals with dental local anaesthesia allergies must be excluded.
  • Patients with respiratory tract infections or lung diseases; There is a potential increased susceptibility for paediatric patients to experience unfavourable respiratory tract effects following exposure to essential oils such as lavender and chamomile. The literature has demonstrated that upon inhalation, essential oils has the ability to effectively penetrate both the upper and lower regions of the respiratory tract
  • Patients with systemic problems; Lavender and chamomile essential oils may cause side effects in children with systemic diseases including impaired immune systems or chronic illnesses. Epidemiological studies have revealed no link between lavender essential oils and endocrine disturbance in youngsters. Children routinely exposed to these essential oils have similar endocrine abnormalities as those who are not .

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (1)

  • Ebrahimi H, Mardani A, Basirinezhad MH, Hamidzadeh A, Eskandari F. The effects of Lavender and Chamomile essential oil inhalation aromatherapy on depression, anxiety and stress in older community-dwelling people: A randomized controlled trial. Explore (NY). 2022 May-Jun;18(3):272-278. doi: 10.1016/j.explore.2020.12.012. Epub 2021 Jan 9.

    PMID: 33454232BACKGROUND

MeSH Terms

Conditions

Anxiety Disorders

Condition Hierarchy (Ancestors)

Mental Disorders

Study Officials

  • Adel Albardisy, professor

    Cairo University

    STUDY DIRECTOR

Central Study Contacts

Sara Ibrahim El Sherbini, master

CONTACT

Reem wahby, phd

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
OTHER
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
principal investigator

Study Record Dates

First Submitted

November 9, 2023

First Posted

November 18, 2023

Study Start

December 1, 2023

Primary Completion

June 1, 2024

Study Completion

September 1, 2024

Last Updated

November 18, 2023

Record last verified: 2023-11

Data Sharing

IPD Sharing
Will not share