Brain Lesion and Visuospatial Impairment in CP Child

NCT06131320 | Completed

• 1 other identifier: 69HCL23_1053
• Study Type: observational
• Target: 150
• Locations: 1 country
• Sites: 1

Brief Summary

Children with cerebral palsy (CP) show varying degrees of motor impairment and movement disorders whose perceptive-visual contribution has yet to be established. The literature reports that children with CP have more frequent neuro-visual disorders. The link between the location and size of the brain lesion and neurovisual symptomatology has yet to be explored. In this retrospective clinical data study, we will investigate in children with PC whether there is an anatomo-clinical correlation between visuo-spatial disorders is the brain injury of interest to the dorsal visual pathway. We will explore the volume of grey and white matter parietal involvement. To test visuo-spatial disorders, we will use the PVSE (Visuo-Spatial Elementary Perception) test which does not require motor skills or language and is therefore suitable for children with a PC. This test will make it possible to better identify the deficit or deficits in order to adapt an early remediation. It could serve as a reference for comparing several pathologies/etiologies.

Conditions

Children with Cerebral Palsy

Keywords

Cerebral Palsy, child, visuo-spatial disorder, brain lesion

Outcome Measures

Primary Outcomes (1)

• PVSE test results: total score and 8 sub-scores (length perception, size perception, angle comparison, midline localization, position perception, position selection, occipital score and parietal score.)

  Using normative values of PVSE test, we assess pathological measure inferior outlier limits and subnormal measure below the lower quartile limit

  At the inclusion

Study Arms (2)

CP child

Diagnostic Test: PVSE Test; Other: Cerebral MRI

CP child with a PVSE test and a cerebral MRI performed during his/her follow-up

Diagnostic Test: PVSE Test; Other: Cerebral MRI

Interventions

PVSE Test DIAGNOSTIC_TEST

Completion of the PVSE test

CP child; CP child with a PVSE test and a cerebral MRI performed during his/her follow-up

Cerebral MRI OTHER

Cerebral MRI scan

CP child; CP child with a PVSE test and a cerebral MRI performed during his/her follow-up

Eligibility Criteria

• Age: 4 Years - 18 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Children coming for out-patient consultation at the paediatric rehabilitation unit of the Hospices Civils de Lyon for a CP diagnosis

You may qualify if:

• Male or female aged 4 to 18 yo
• With a CP diagnosis
• With PVSE test completion during his/her regular follow-up
• With a cerebral MRI scan during his/her regular follow-up

You may not qualify if:

• \- With an incomplete PVSE test or whose interpretation was deemed unreliable by the rater

Sponsors & Collaborators

• Hospices Civils de Lyon: lead

Study Sites (1)

Pediatric rehabilitation unit of the Hospices Civils de Lyon

Bron, 69677, France

Location

MeSH Terms

Conditions

Cerebral Palsy

Condition Hierarchy (Ancestors)

Brain Damage, Chronic; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: November 9, 2023
• First Posted: November 14, 2023
• Study Start: September 1, 2022
• Primary Completion: December 31, 2023
• Study Completion: April 2, 2024
• Last Updated: November 8, 2024

Record last verified: 2024-11

Data Sharing

• IPD Sharing: Will not share

Locations

FR (1)