NCT06114199

Brief Summary

Harris Health System is currently participating, along with two other partners, GoldiFresh Inc., and Brighter Bites, in a cross-sector collaborative home delivery-based Produce Prescription Program (PPRx) pilot initiative that provides consistent access to healthy food plus nutrition education to Medicaid-eligible pregnant women in Harris County, TX, deemed to be at high risk of adverse pregnancy or birth outcomes. The objectives of this study are two-fold: (a) to examine utilization of food basket contents and improvements in diet quality in this home delivery based PPRx program, and (b) to evaluate if and the extent to which utilization of food basket contents outcomes improves with support from an interactive AI-based conversational agent to convert food into healthy meals.

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
200

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Jul 2024

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

October 27, 2023

Completed
6 days until next milestone

First Posted

Study publicly available on registry

November 2, 2023

Completed
9 months until next milestone

Study Start

First participant enrolled

July 26, 2024

Completed
1.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 25, 2025

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

November 25, 2025

Completed
Last Updated

July 15, 2025

Status Verified

July 1, 2025

Enrollment Period

1.3 years

First QC Date

October 27, 2023

Last Update Submit

July 9, 2025

Conditions

Outcome Measures

Primary Outcomes (2)

  • Change in consumption of home-delivered produce from baseline to 6 months

    7 point rating scale ranging from 0=none to 6=all, assessing what proportion of delivered produce was consumed over the past two weeks.

    Measures will be collected at baseline, and 6 times at random intervals over the next 6 months

  • Change in usual consumption of fruits and vegetables from baseline to 6 months

    Fruit and vegetable consumption scale, measured by NCI dietary screener. Scale includes multiple sources of fruit and vegetables in diet, and is scored in terms of cups of fruit / day, and cups of vegetables / day

    Measures will be collected at baseline, and after 6 months of exposure to program

Study Arms (2)

Produce Prescription Program (PPRx) Standard

ACTIVE COMPARATOR

Participants will receive biweekly deliveries of 20 lbs (\~50 servings) of fresh produce (8-10 different kinds of produce) plus standard nutrition education materials consisting of nutrition education infographics inside of the produce prescription boxes as well as online videos, recipes, and nutrition tips accessed via Quick Response (QR) code.

Behavioral: Produce Prescription Program (PPRx) Standard

Produce Prescription Program (PPRx) Standard plus Smartphone App

EXPERIMENTAL

Participants will receive biweekly deliveries of 20 lbs (\~50 servings) of fresh produce (8-10 different kinds of produce) plus the same standard nutrition education materials provided to the control group consisting of nutrition education infographics inside of the produce prescription boxes as well as online videos, recipes, and nutrition tips accessed via Quick Response (QR) code. Additionally, participants will be given access to a smartphone app that allows women to interact with an artificial intelligence (AI) chatbot to obtain real-time cooking suggestions.

Behavioral: Produce Prescription Program (PPRx) StandardBehavioral: Smartphone App

Interventions

Participants will receive biweekly deliveries of 20 lbs (\~50 servings) of fresh produce (8-10 different kinds of produce) plus standard nutrition education materials consisting of nutrition education infographics inside of the produce prescription boxes as well as online videos, recipes, and nutrition tips accessed via Quick Response (QR) code.

Produce Prescription Program (PPRx) StandardProduce Prescription Program (PPRx) Standard plus Smartphone App
Smartphone AppBEHAVIORAL

Participants will be given access to a smartphone app that allows women to interact with an artificial intelligence (AI) chatbot to obtain real-time cooking suggestions.

Produce Prescription Program (PPRx) Standard plus Smartphone App

Eligibility Criteria

Age18 Years - 44 Years
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • receiving prenatal care at high-risk obstetric clinics
  • \<= 20 weeks medically-confirmed viable pregnancy
  • designated as high risk \[Age\>=35 years, or obese or overweight (BMI\>=25.0 at pre pregnancy self-report), or prior history of pregnancy hypertension or gestational diabetes\]
  • within the zip code delivery radius

You may not qualify if:

  • women who were medically recommended bed rest through pregnancy
  • substance users

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

The University of Texas Health Science Center at Houston

Houston, Texas, 77030, United States

RECRUITING

Study Officials

  • Nanlini Ranjit, PhD

    The University of Texas Health Science Center, Houston

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Professor

Study Record Dates

First Submitted

October 27, 2023

First Posted

November 2, 2023

Study Start

July 26, 2024

Primary Completion

November 25, 2025

Study Completion

November 25, 2025

Last Updated

July 15, 2025

Record last verified: 2025-07

Data Sharing

IPD Sharing
Will share

At the end of the project, de-identified data at individual level will be uploaded to the American Heart Association (AHA) Precision-Medicine Platform.

Shared Documents
STUDY PROTOCOL, SAP, ICF
Time Frame
September 30, 2024
Access Criteria
Will be determined by AHA.

Locations