Assessment of Maximal Oxygen Uptake in Cardiac Rehabilitation

NCT06113133 | Completed DMC

• 1 other identifier: 9000035
• Study Type: observational
• Target: 97
• Locations: 1 country
• Sites: 1

Brief Summary

To advance the methodology for evaluating persons with heart disease and their maximal oxygen uptake, the primary aim of this study is to investigate the occurrence of a plateau in oxygen uptake. This plateau will be examined for the purpose of assessing VO2 max in persons enrolled in exercise-based cardiac rehabilitation. Furthermore, this study aims to investigate the age-related respiratory exchange ratio, and rating of perceived exertion, and describe their association with the presence of a plateau. Heart disease and characteristics for all participants are obtained. Participants underwent a maximal exercise test on an ergometer cycle with direct measurement of oxygen uptake to assess oxygen plateau attainment. This included measurement of the maximal oxygen uptake, respiratory exchange ratio, heart rate and the ratio of perceived exertion (BORG6-20).

Conditions

Oxygen Consumption

Keywords

Physical fitness; heart disease; oxygen consumption

Outcome Measures

Primary Outcomes (1)

• Maximal oxygen uptake

  Cardiopulmonary exercise test by Metalyzer 3B to determine maximal oxygen uptake measured in millimetre oxygen

  Pretest is conducted at the first day in rehabilitation. Posttest is conducted when a participant finish rehabilitation or maximal 1 week after the end of the rehabilitation after 12-weeks

Secondary Outcomes (3)

• Respiratory exchange ratio

  Respiratory exchange ratio is measured during CPET at pretest the first day in rehabilitation. Posttest is conducted the last week of rehabilitation or maximal 1 week after ending the 12-week program.

• Ratio of perceived exertion

  The participants rate their perceived exertion immediately after CPET is finished at pretest the first day in rehabilitation. Posttest is conducted the last week of rehabilitation or maximal 1 week after ending the 12-week program.

• Maximal heart rate

  Heart rate is measured during CPET at pretest the first day in rehabilitation. Posttest is conducted the last week of rehabilitation or maximal 1 week after ending the 12-week program.

Study Arms (1)

Maximal oxygen uptake

Measurement of maximal oxygen uptake using \< 50-millilitre and 100 millilitre oxygen as a cut-off

Diagnostic Test: measurement of oxygen uptake

Interventions

measurement of oxygen uptake DIAGNOSTIC_TEST

oxygen uptake is obtained during a maximal exercise test

Maximal oxygen uptake

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Participants are adults with heart diseases such as ischemia, heart failure and after heart valve surgery

You may qualify if:

• participants with heart disease referred to exercise-based cardiac rehabilitation in primary healthcare settings were included

You may not qualify if:

• heart-related symptoms according to clinical guidelines that prevent participants from performing a maximal exercise test.

Sponsors & Collaborators

• VIA University College: lead

Study Sites (1)

Claus Sevel

Aarhus N, 8200, Denmark

Location

MeSH Terms

Conditions

Heart Diseases

Condition Hierarchy (Ancestors)

Cardiovascular Diseases

Study Officials

• Maribo, Professor

  University of Aarhus

  STUDY CHAIR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: OTHER
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 22, 2023
• First Posted: November 2, 2023
• Study Start: December 1, 2022
• Primary Completion: May 31, 2023
• Study Completion: May 31, 2023
• Last Updated: November 2, 2023

Record last verified: 2023-10

Data Sharing

• IPD Sharing: Will not share

Locations

DK (1)