Corneal High Order Aberrations After Stream Light and Mechanical Photorefractive Keratectomy
Comparison of Corneal High Order Aberrations After Stream Light Trans-PRK and Mechanical Photorefractive Keratectomy
1 other identifier
observational
60
1 country
1
Brief Summary
Compare corneal high order aberrations before and after stream light trans-PRK and mechanical photorefractive keratectomy including third order aberrations; Trefoil and coma aberrations and forth order aberrations; spherical aberrations
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for all trials
Started Nov 2023
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
October 26, 2023
CompletedFirst Posted
Study publicly available on registry
October 31, 2023
CompletedStudy Start
First participant enrolled
November 1, 2023
CompletedPrimary Completion
Last participant's last visit for primary outcome
October 1, 2024
CompletedStudy Completion
Last participant's last visit for all outcomes
October 1, 2025
CompletedOctober 31, 2023
October 1, 2023
11 months
October 26, 2023
October 26, 2023
Conditions
Outcome Measures
Primary Outcomes (1)
Corneal high order aberrations measured before and after the intervention by corneal topography machine
* Third order aberrations; Trefoil and coma aberrations * Forth order aberrations; spherical aberrations Trefoil, spherical and coma aberrations
1 monthe after surgery
Study Arms (2)
Mechanical photorefractive keratectomy
Laser photorefractive keratecyomy by Ex500 excimer laser after mannual removal of corneal epithelium
Stream light trans-PRK
Laser photorefractive keratectomy by Ex500 excimer laser after removal of corneal epithelium by stream-light laser technique
Interventions
Laser keratectomy by EX500 excimer laser after removal of corneal epithelium either mannually or by laser ablation
Eligibility Criteria
Myopic patients with spherical equivalent not more than -6D who will present to refractive surgery Centre in Assiut and seeking for refractive surgery to get rid of their glasses and fulfilling the inclusion and exclusion criteria
You may qualify if:
- Stable refraction for 1 year (refraction does not exceed 1D more than the last prescribed glasses).
- Discontinuation of soft contact lens wears at least 1 week before examination.
- Topography criteria:
- Corneal thickness equal or more than 470 um
- Symmetrical bow-tie
- Back elevation not more than +12
- Normal Belin\\Ambrosio Enhanced ectasia display
- Spherical equivalent not more than -6D.
You may not qualify if:
- Previous ocular surgery
- Concurrent ocular pathology; corneal scar, corneal dystrophy
- Systemic disease; Uncontrolled diabetes, collagen disease
- Post-operative complications; sub-epithelial haze.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Assiut university faculty of medicine
Asyut, Assiut University, 71515, Egypt
MeSH Terms
Interventions
Intervention Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Associate professor
Study Record Dates
First Submitted
October 26, 2023
First Posted
October 31, 2023
Study Start
November 1, 2023
Primary Completion
October 1, 2024
Study Completion
October 1, 2025
Last Updated
October 31, 2023
Record last verified: 2023-10