Feasibility of Physical Activity in Older Adults With Haematological Malignancies: ACCES Study

NCT06102876 | Active Not Recruiting

• 1 other identifier: RC31/23/0409
• Study Type: observational
• Target: 69
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this study is to implement a simple and unsupervised home-based physical activity (PA) program for cancer patients in 2 oncogeriatric units in Toulouse Hospital (day hospital and week hospital).

Conditions

Geriatric; Haematologic Neoplasm

Keywords

older adults; cancer; physical activity; deconditioning; sedentarity; aging-well

Outcome Measures

Primary Outcomes (1)

• Feasibility of the PA program

  PA program is considered feasible if at least 50% of them complete at least 70% of the prescribed sessions. Adherence is recorded in a logbook (every day), during the usual follow-up at the hospital (every month) and during telephone follow-up (weeks 1, 2, 4, 6, 9, 12, 16, 20, et 24).

  6 months

Interventions

Physical activity (PA) program OTHER

The PA program is specific for each patient according to their mobility profile assessed using a decision tree comprising 3 tests: 1) the number of repetitions in the 30-second sit-to-stand test, 2) the score in the Short Physical Performance Battery (SPPB) test and 3) grip strength. The PA program has to be performed once daily.

Eligibility Criteria

• Age: 65 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

geriatric population suffering from a hematological malignancy (Myelodysplasia, Leukemia of any type, Lymphoma, Myeloma

You may qualify if:

• suffering from a hematological malignancy (Myelodysplasia, Leukemia of any type, Lymphoma, Myeloma)
• patient affiliated to a social security insurance
• Patient undergoing or scheduled chemotherapy (\< 3 months) and/or immunotherapy and/or targeted therapy.

You may not qualify if:

• Life expectancy estimated at less than 3 months by the unit doctor;
• Cognitive impairment (not allowing comprehension of the physical activity program and research project) defined by Mini-Mental State Examination (MMSE) \<20/30;
• Patient included in a clinical trial that potentially interferes with the study objective (geriatric interventional study, early drug study, study modifying the patient's lifestyle habits).;
• Acute health problem (fever, severe anemia, intense pain, etc.) limiting the possibility of involvement in the program;
• Contraindication to physical activity;
• Patient under legal protection (guardianship or curatorship or safeguard of justice);
• Refusal of patient or primary caregiver to participate.

Sponsors & Collaborators

• University Hospital, Toulouse: lead

Study Sites (1)

Chu de Toulouse

Toulouse, France

Location

MeSH Terms

Conditions

Hematologic Neoplasms; Neoplasms; Motor Activity

Interventions

Exercise

Condition Hierarchy (Ancestors)

Neoplasms by Site; Hematologic Diseases; Hemic and Lymphatic Diseases; Behavior

Intervention Hierarchy (Ancestors)

Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Officials

• Yves Rolland

  University Hospital, Toulouse

  STUDY DIRECTOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: October 20, 2023
• First Posted: October 26, 2023
• Study Start: November 14, 2023
• Primary Completion: September 30, 2025
• Study Completion: September 30, 2025
• Last Updated: April 10, 2025

Record last verified: 2025-04

Locations

FR (1)