New Diagnostic Markers In Dignosis Of Complicated Appendix
1 other identifier
interventional
50
1 country
1
Brief Summary
Most common cause of acute abdomen is acute appendicitis delay dignosis of acute appendicitis lead to complications as perforation this study examined efficacy of hyperbilirubinemia\&hyponatremia as indicator of complicated appendicitis
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable
Started Oct 2023
Shorter than P25 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
October 1, 2023
CompletedFirst Submitted
Initial submission to the registry
October 22, 2023
CompletedFirst Posted
Study publicly available on registry
October 26, 2023
CompletedPrimary Completion
Last participant's last visit for primary outcome
March 31, 2024
CompletedStudy Completion
Last participant's last visit for all outcomes
March 31, 2024
CompletedOctober 26, 2023
October 1, 2023
6 months
October 22, 2023
October 25, 2023
Conditions
Outcome Measures
Primary Outcomes (3)
Level of bilirubin in acute appendicitis
6 months
Level of sodium in acute appendicitis
6 months
Level of c-reactive proteins in acute appendicitis
6 months
Interventions
detect level of bilirubin,sodium \&c-reactive protein as indicator of complicated appendicitis
Eligibility Criteria
You may qualify if:
- all patient admitted for acute appendicitis underwent surgery and post operativly confirmed histopathology of acute appendicitis
You may not qualify if:
- patient with liver disease Liver transplantation Chronic alcoholism Congental biliary disease Pregnancy Appendicular neoplasm Hemolytic disease Hepatocellular carcinoma
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Sohag Universitylead
Study Sites (1)
Sohag University hospital
Sohag, Egypt
Related Publications (4)
Virmani S, Prabhu PS, Sundeep PT, Kumar V. Role of laboratory markers in predicting severity of acute appendicitis. Afr J Paediatr Surg. 2018 Jan-Mar;15(1):1-4. doi: 10.4103/ajps.AJPS_47_16.
PMID: 30829300BACKGROUNDKar S, Behera TK, Jena K, Sahoo AK. Hyperbilirubinemia as a Possible Predictor of Appendiceal Perforation in Acute Appendicitis: A Prospective Study. Cureus. 2022 Feb 2;14(2):e21851. doi: 10.7759/cureus.21851. eCollection 2022 Feb.
PMID: 35282512BACKGROUNDAlvarado A. A practical score for the early diagnosis of acute appendicitis. Ann Emerg Med. 1986 May;15(5):557-64. doi: 10.1016/s0196-0644(86)80993-3.
PMID: 3963537BACKGROUNDKanumba ES, Mabula JB, Rambau P, Chalya PL. Modified Alvarado Scoring System as a diagnostic tool for acute appendicitis at Bugando Medical Centre, Mwanza, Tanzania. BMC Surg. 2011 Feb 17;11:4. doi: 10.1186/1471-2482-11-4.
PMID: 21329493BACKGROUND
Central Study Contacts
Omar A Syed, Professor
CONTACT
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NA
- Masking
- NONE
- Purpose
- DIAGNOSTIC
- Intervention Model
- SINGLE GROUP
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Residiant in general surgery department
Study Record Dates
First Submitted
October 22, 2023
First Posted
October 26, 2023
Study Start
October 1, 2023
Primary Completion
March 31, 2024
Study Completion
March 31, 2024
Last Updated
October 26, 2023
Record last verified: 2023-10