The Effect of Exercise on Brain Functions

NCT06099483 | Completed

• 1 other identifier: ebraratak1
• Study Type: interventional
• Target: 33
• Locations: 1 country
• Sites: 1

Brief Summary

Concept of action simulation; It is an internal representation of motor programs that does not involve explicit movement. Motor imagery method (MI) or movement observation (HG) method are considered two separate action simulation methods that activate motor regions in the brain. Both methods remain a popular and effective tool for improving motor learning. Research has shown that clinicians working in rehabilitation settings are aware of the needs of patients, athletes, etc. are recommended as methods that participants can use to improve their motor skills. Motor imagery training is a dynamic mental process in which a movement is mentally visualized without any visible movement or any voluntary motor muscle activation. Movement observation training is a method that involves internal, real-time motor simulation of movements in which the observer visually perceives movements performed by another. Mirror neurons, located primarily in the rostral part of the inferior parietal lobe and the ventral premotor cortex, are activated both when an action is physically performed and when the action is observed being performed by another person. Studies using neuroimaging techniques have provided support for this theory by showing that many areas known to be active during action simulation, such as the dorsal pre-motor cortex, supplementary motor area, superior parietal lobe, and intraparietal sulcus, are indeed active during both HG and MI. There is evidence in the literature that MI and HG also trigger sympathetic nervous system activation. There may be changes in respiration, heart rate and skin temperature, as well as an increase in electrodermal activity. EEG is an inexpensive, noninvasive, and simple examination that can be used to evaluate neurophysiological functions by measuring electrical activity. Understanding the mechanism of beta rhythms is important because they are associated with conscious thinking, logical thinking, memory and problem solving, whereas suppression of beta waves contributes to depression and cognitive decline. This study will investigate the effectiveness of exercising or watching or imagining exercise on brain functions.

Conditions

Pulmonary; EEG

Keywords

motor imagery; EEG; pulmonary rehabilitation

Outcome Measures

Primary Outcomes (1)

• Acute effect on brain electrical activity

  Motor imagery exercise combined with action observation has an acute effect on brain electrical activity in healthy sedentary individuals.

  up to 24 weeks

Secondary Outcomes (1)

• Acute effect on cardioventilatory responses

  up to 24 weeks

Study Arms (3)

action observation and motor imegary

ACTIVE COMPARATOR

The motor imagery and action observation group was asked to watch a previously recorded breathing exercise video and imagine it as if they were doing it themselves.

Other: Action observation and motor imagery

Active Breathing Exercise Group

ACTIVE COMPARATOR

Respiratory control, diaphragmatic breathing and thoracic expansion exercises were actively performed for 10 repetitions each.

Other: Active breathing exercise

Control group

ACTIVE COMPARATOR

Participants will remain in a sitting position throughout the entire experimental group application. Participants were prevented from making physical movements and were asked to keep their minds closed by closing their eyes and not thinking about anything.

Other: Control group

Interventions

Action observation and motor imagery OTHER

EEG recording was taken while watching a 10-minute video recording of specified breathing exercises and imagining the exercises.

action observation and motor imegary

Active breathing exercise OTHER

EEG recording was taken while the physiotherapist performed active breathing exercises for 10 minutes.

Active Breathing Exercise Group

Control group OTHER

EEG recording was taken while resting with eyes closed for 10 minutes.

Control group

Eligibility Criteria

• Age: 18 Years - 55 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Volunteering to participate in the study
• Being between the ages of 18-40
• Not using an assistive device
• Having been using the same medications for the last 4 weeks
• No additional comorbid diseases of the orthopedic, neurological or cardiac system
• Getting 30 or more points from each of the Kinesthetic and Visual Imagination Questionnaire -20 (KGIA-20) visual imagination score and kinesthetic imagination score (The purpose of this criterion is to check that the patients who will be distributed to the cognitive rehabilitation group have sufficient imagination ability and to be able to do the exercises.)

You may not qualify if:

• Not agreeing to participate in the study
• Patients who have used oral corticosteroid drugs in the last 4 weeks
• Participants who cannot understand verbal instructions and are visually impaired
• Have currently participated in another clinical trial within the last 30 days that may affect the results of the study

Sponsors & Collaborators

• Istanbul Medipol University Hospital: lead
• Istanbul Gedik University: collaborator

Study Sites (1)

Ebrar Atak

Yalova, 77100, Turkey (Türkiye)

Location

Related Publications (1)

• Atak E, Atac A. The Acute Effects of Motor Imagery Combined With Action Observation Breathing Exercise on Cardiorespiratory Responses, Brain Activity, and Cognition: A Randomized, Controlled Trial. Cardiovasc Ther. 2025 Feb 22;2025:6460951. doi: 10.1155/cdr/6460951. eCollection 2025.

  PMID: 40026414 DERIVED

MeSH Terms

Interventions

Control Groups

Intervention Hierarchy (Ancestors)

Epidemiologic Research Design; Epidemiologic Methods; Investigative Techniques; Research Design; Methods

Study Officials

• Ebrar Atak, PhD

  Istanbul Gedik University

  STUDY DIRECTOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: TRIPLE
• Who Masked: PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
• Purpose: BASIC SCIENCE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor

Model Details: randomized controlled double-blind study

Study Record Dates

• First Submitted: October 16, 2023
• First Posted: October 25, 2023
• Study Start: August 1, 2023
• Primary Completion: September 30, 2023
• Study Completion: September 30, 2023
• Last Updated: March 22, 2024

Record last verified: 2024-03

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)