The Effect Of Baby Smell On The Amount Of Breast Milk, Salivary Cortisol Level And Mother Baby Attachment

NCT06096961 | Unknown

• 1 other identifier: OYKUCALISMA
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this \[type of study: randomized controlled clinical trial\] is to \[determine the effect of applying the scent of premature newborns who cannot be breastfed to the mother on the mother's milk amount, salivary cortisol level and mother-infant attachment.\] in \[mothers of premature babies\]. The main question\[s\] it aims to answer are:

• \[Hypothesis 1: There is a difference in the amount of milk of the mother.\]
• \[Hypothesis 2: There is a difference in the level of cortisol in the mother's saliva.\]
• \[Hypothesis 3: There is a difference in terms of mother-baby attachment level.\] Participants will \[Participants will express milk and record the amount of milk.\]. If there is a comparison group: Researchers will compare \[control and experimental groups\] to see if \[difference in amount of milk, cortisol level, baby attachment\].

Conditions

Mother-Infant Interaction; Premature Birth

Keywords

mother milk; stress; mother baby bonding; premature

Outcome Measures

Primary Outcomes (1)

• amount of breast milk

  Mothers participating in the study will express their milk every three hours for four days and record the amount of milk.

Secondary Outcomes (2)

• mother baby attachment scale

  The mother-infant attachment scale will be applied to the mothers participating in the study on the first and fourth day of the study.

• salivary cortisol level

  Saliva cortisol test will be applied to the mothers participating in the study on the first and fourth day of the study.

Study Arms (2)

Mothers using baby scent

EXPERIMENTAL

Mothers in the experimental group will be given baby clothes that their babies will wear for 12 hours and will be asked to smell these clothes during the milking process. The work will continue for four days. Saliva cortisol test and mother-infant attachment scale will be applied on the first day and the last day.

Behavioral: Baby smell

Mothers who do not use baby scent

NO INTERVENTION

Mothers in the control group will express milk without any intervention. The works will continue for 4 days. Saliva cortisol test and mother-baby attachment scale will be applied on the first day and the last day.

Interventions

Baby smell BEHAVIORAL

Mothers in the experimental group will be given baby clothes that their babies will wear for 12 hours and will be asked to smell these clothes during the milking process.

Mothers using baby scent

Eligibility Criteria

• Gender Eligibility Details: Only mothers can participate in the study.
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• Mother's acceptance of the application
• Ability to communicate with the mother (being literate, speaking Turkish, etc.)
• Gestational week being 34 weeks or less
• The newborn is in the NICU

You may not qualify if:

• The newborn's gestational age is over 34 weeks
• The mother is breastfeeding her baby
• Being a smoker (Ahmed et al. 2019)
• The mother is unable to express milk due to a serious chronic disease or pregnancy complication.
• The mother has a breast problem that may affect milk expression (cracked, mastitis, collapse, etc.).
• If the mother uses milk-boosting drinks or food

Sponsors & Collaborators

• Eskisehir Osmangazi University: lead

Study Sites (1)

Eskisehir Osmangazi University

Eskişehir, 26000, Turkey (Türkiye)

Location

Related Publications (21)

• Akkoca Z, Yigit D, Acikgoz A. The Effect of Neonates' Exposure to Their Mother's Scent on Weight Gain: A Randomized Controlled Study. Breastfeed Med. 2022 Jan;17(1):79-84. doi: 10.1089/bfm.2021.0274. Epub 2021 Dec 22.

  PMID: 34939823 BACKGROUND

• Cakirli M, Acikgoz A. A Randomized Controlled Trial: The Effect of Own Mother's Breast Milk Odor and Another Mother's Breast Milk Odor on Pain Level of Newborn Infants. Breastfeed Med. 2021 Jan;16(1):75-81. doi: 10.1089/bfm.2020.0222. Epub 2020 Oct 20.

  PMID: 33085532 BACKGROUND

• Chrustek A, Dombrowska-Pali A, Olszewska-Slonina D. Analysis of the composition and antioxidant status of breast milk in women giving birth prematurely and on time. PLoS One. 2021 Jul 23;16(7):e0255252. doi: 10.1371/journal.pone.0255252. eCollection 2021.

  PMID: 34297788 BACKGROUND

• Holditch-Davis D, Santos H, Levy J, White-Traut R, O'Shea TM, Geraldo V, David R. Patterns of psychological distress in mothers of preterm infants. Infant Behav Dev. 2015 Nov;41:154-63. doi: 10.1016/j.infbeh.2015.10.004. Epub 2015 Oct 22.

  PMID: 26495909 BACKGROUND

• Ak J, Lakshmanagowda PB, G C M P, Goturu J. Impact of music therapy on breast milk secretion in mothers of premature newborns. J Clin Diagn Res. 2015 Apr;9(4):CC04-6. doi: 10.7860/JCDR/2015/11642.5776. Epub 2015 Apr 1.

  PMID: 26023551 BACKGROUND

• Miller J, Tonkin E, Damarell RA, McPhee AJ, Suganuma M, Suganuma H, Middleton PF, Makrides M, Collins CT. A Systematic Review and Meta-Analysis of Human Milk Feeding and Morbidity in Very Low Birth Weight Infants. Nutrients. 2018 May 31;10(6):707. doi: 10.3390/nu10060707.

  PMID: 29857555 BACKGROUND

• Montirosso R, Provenzi L, Calciolari G, Borgatti R; NEO-ACQUA Study Group. Measuring maternal stress and perceived support in 25 Italian NICUs. Acta Paediatr. 2012 Feb;101(2):136-42. doi: 10.1111/j.1651-2227.2011.02440.x. Epub 2011 Sep 14.

  PMID: 21827551 BACKGROUND

• Neu M, Hazel NA, Robinson J, Schmiege SJ, Laudenslager M. Effect of holding on co-regulation in preterm infants: a randomized controlled trial. Early Hum Dev. 2014 Mar;90(3):141-7. doi: 10.1016/j.earlhumdev.2014.01.008. Epub 2014 Jan 27.

  PMID: 24480604 BACKGROUND

• Rojas MA, Kaplan M, Quevedo M, Sherwonit E, Foster L, Ehrenkranz RA, Mayes L. Somatic growth of preterm infants during skin-to-skin care versus traditional holding: a randomized, controlled trial. J Dev Behav Pediatr. 2003 Jun;24(3):163-8. doi: 10.1097/00004703-200306000-00006.

  PMID: 12806228 BACKGROUND

• Tasci B, Kuzlu Ayyildiz T. The Calming Effect of Maternal Breast Milk Odor on Term Infant: A Randomized Controlled Trial. Breastfeed Med. 2020 Nov;15(11):724-730. doi: 10.1089/bfm.2020.0116. Epub 2020 Oct 29.

  PMID: 33121256 BACKGROUND

• Taylor A, Atkins R, Kumar R, Adams D, Glover V. A new Mother-to-Infant Bonding Scale: links with early maternal mood. Arch Womens Ment Health. 2005 May;8(1):45-51. doi: 10.1007/s00737-005-0074-z. Epub 2005 May 4.

  PMID: 15868385 BACKGROUND

• Trend S, Strunk T, Lloyd ML, Kok CH, Metcalfe J, Geddes DT, Lai CT, Richmond P, Doherty DA, Simmer K, Currie A. Levels of innate immune factors in preterm and term mothers' breast milk during the 1st month postpartum. Br J Nutr. 2016 Apr 14;115(7):1178-93. doi: 10.1017/S0007114516000234. Epub 2016 Feb 19.

  PMID: 26891901 BACKGROUND

• Ahmed, F., Jean-Baptiste, F., Thompson, A., Nwokorie, U., Nya, G. E., & Bassey, G. O. . Effects of maternal tobacco smoking on breast milk composition and infant development: a literature review. J Bacteriol Mycol Open Access. 2019; 7(5): 107-110.

  BACKGROUND

• Aydemir Karakulak, H, Alparslan, Ö. Anne-bebek bağlanma ölçeğinin türk toplumuna uyarlanması: Aydın örneği . Çağdaş Tıp Dergisi. 2016; 6 (3) : 188-199 .

  BACKGROUND

• Dabas S, Joshi P, Agarwal R, Yadav RK, & Kachhawa G. Impact of audio assisted relaxation technique on stress, anxiety and milk output among postpartum mothers of hospitalized neonates: A randomized controlled trial. Journal of Neonatal Nursing. 2019; 25(4): 200-204.

  BACKGROUND

• De Clifford-Faugère G, Aita M, Héon M,& Le May S. Management of procedural pain in preterm infants through olfactive stimulation with mothers' milk: A pilot study. Science of Nursing and Health Practices. 2019; 2(1): 1-13.

  BACKGROUND

• Kömürcü B. Erken doğan bebek annelerinde travma sonrası stres: ilişkili etmenler ve müdahale çalışmaları üzerine bir derleme. Nesne-Psikoloji Dergisi. 2020; 8(16): 158-170.

  BACKGROUND

• Merter ÖS, Altay N. Yenidoğan yoğun bakımda izlenen prematüre bebeklerin anne sütü ile beslenme durumlarının değerlendirilmesi. Gazi Sağlık Bilimleri Dergisi. 2020; 5 (1): 21-29.

  BACKGROUND

• Özlü F, Tunç A, Yıldızdaş HY, & Büyükkurt S. Geç prematüre doğan bebeklerin postnatal ilk 15 günde karşılaştıkları sorunların değerlendirilmesi. Çocuk Sağlığı ve Hastalıkları Dergisi. 2017; 60(2): 39-54.

  BACKGROUND

• Suzan ÖK. Kolostrum: Özellikleri ve prematüre bebeğe faydaları. Sürekli Tıp Eğitimi Dergisi. 2020; 29(3): 221-227

  BACKGROUND

• Varışoğlu Y, Güngör Satılmış İ. Preterm doğumlarda anne sütü ve anne sütünü artırmaya yönelik alternatif yöntemler . Izmir Democracy University Health Sciences Journal. 2019; 2 (2): 99-113 .

  BACKGROUND

Related Links

• Related Info
• Related Info
• Related Info

MeSH Terms

Conditions

Premature Birth

Condition Hierarchy (Ancestors)

Obstetric Labor, Premature; Obstetric Labor Complications; Pregnancy Complications; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases

Study Officials

• AYFER ACIKGOZ

  Eskisehir Osmangazi University

  STUDY DIRECTOR

Central Study Contacts

OYKU BALI BILGI

CONTACT

+905074160813; oykubali7@gmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, CARE PROVIDER
• Purpose: HEALTH SERVICES RESEARCH
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Model Details: There are two groups in the study: experimental and control groups. Mothers in the experimental group will be given baby clothes that their babies will wear for 12 hours and will be asked to smell these clothes during the milking process. The work will continue for four days. Mothers in the intervention group will smell their baby's scented diapers, and mothers in the control group will express their milk without any intervention and record the amount.

Study Record Dates

• First Submitted: October 4, 2023
• First Posted: October 24, 2023
• Study Start: November 1, 2023
• Primary Completion: April 1, 2024
• Study Completion: April 1, 2024
• Last Updated: October 24, 2023

Record last verified: 2023-10

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)