Multiple Myeloma Prognostic Indices

NCT06095752 | Completed

• 1 other identifier: MM prognosis
• Study Type: observational
• Target: 48
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this study was to evaluate the impact of albumin / fibrinogen ratio, blood viscosity and RDW on the prognosis of a newly diagnosed MM patients

Conditions

Multiple Myeloma; Hematologic Diseases

Outcome Measures

Primary Outcomes (3)

• Determine the prognosis of newly diagnosed multiple myeloma patients in survival for one year.

  After initial diagnosis of a patient to have multiple myeloma , blood viscosity is obtained and within a year , a relation is established between the prognosis of the disease and the initial results of blood viscosity

  One year

• Determine the prognosis of newly diagnosed multiple myeloma patients in survival for one year.

  After initial diagnosis of a patient to have multiple myeloma , albumin / fibrinogen ratio is obtained and within a year , a relation is established between the prognosis of the disease and the initial results of albumin /fibrinogen ratio

  One year

• Determine the prognosis of newly diagnosed multiple myeloma patients in survival for one year.

  After initial diagnosis of a patient to have multiple myeloma , red cell distribution is obtained and within a year , a relation is established between the prognosis of the disease and the initial results of red cell distribution

  One year

Interventions

blood viscosity , albumin / fibrinogen ratio and red cell distribution OTHER

In multiple myeloma patients ,we get blood viscosity , albumin / fibrinogen ratio and red cell distribution directly after confirmed diagnosis to determine the prognosis of the disease in association with these tests results

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

based on study methodology , the studied population (who are the newly diagnosed cases ) will be followed up to one year after diagnosis to report outcomes . the researcher will recruit the newly diagnosed cases who seek care at internal medicine department, assiut university hospital in completed one year duration and then follow up the case for one year. After reviewing medical record , average flow rate of MM at internal medicine department is 2 cases per month , nearly 25 cases will be included in this study

You may qualify if:

• Patients newly diagnosed with MM according to International Myeloma Working Group criteria 2016.

You may not qualify if:

• Patient previously diagnosed MM and started treatment or in post treatment follow up

Sponsors & Collaborators

• Assiut University: lead

Study Sites (1)

Assiut University hospital

Asyut, Asyut Governorate, 88, Egypt

Location

MeSH Terms

Conditions

Multiple Myeloma; Hematologic Diseases

Interventions

Blood Viscosity; Albumins

Condition Hierarchy (Ancestors)

Neoplasms, Plasma Cell; Neoplasms by Histologic Type; Neoplasms; Hemostatic Disorders; Vascular Diseases; Cardiovascular Diseases; Paraproteinemias; Blood Protein Disorders; Hemic and Lymphatic Diseases; Hemorrhagic Disorders; Lymphoproliferative Disorders; Immunoproliferative Disorders; Immune System Diseases

Intervention Hierarchy (Ancestors)

Hemorheology; Blood Physiological Phenomena; Circulatory and Respiratory Physiological Phenomena; Hemodynamics; Cardiovascular Physiological Phenomena; Proteins; Amino Acids, Peptides, and Proteins

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Resident doctor, Ahmed Radwan abdelhakim

Study Record Dates

• First Submitted: September 27, 2023
• First Posted: October 23, 2023
• Study Start: April 1, 2023
• Primary Completion: April 30, 2025
• Study Completion: April 30, 2025
• Last Updated: October 2, 2025

Record last verified: 2025-04

Locations

EG (1)