NCT06092723|Completed

Effects of Probiotics Improves the Endurance and Explosiveness Exercise Performance on Healthy Human.

Effects of Lactococcus Lactics Subsp. Lactics, LY-66, Lactobacillus Plantarum, PL-02, and Combination LY-66+PL-02 Improves the Endurance and Explosiveness Exercise Performance on Healthy Human.

Glac Biotech Co., Ltd ClinicalTrials.gov

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1 other identifier

LSHIRB21-042-A2

Study Type

interventional

Target

Locations

1 country

Sites

Timeline

RegisteredOct 2023

StartedDec 2021

CompletionFeb 2023

Brief Summary

This study may discover that supplementing with probiotics LY-66, PL-02 can promote exercise endurance, explosive power and reduce muscle inflammation index in healthy people.

Trial Health

On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment

participants targeted

Target at P50-P75 for not_applicable

Timeline

Completed

Started Dec 2021

Geographic Reach

1 country

1 active site

Status

completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

1.2 years study duration

Study Start

First participant enrolled

December 1, 2021

Completed

1.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 7, 2023

Completed

Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

February 7, 2023

Completed

8 months until next milestone

First Submitted

Initial submission to the registry

September 28, 2023

Completed

25 days until next milestone

First Posted

Study publicly available on registry

October 23, 2023

Completed

Last Updated

October 23, 2023

Status Verified

October 1, 2023

Enrollment Period

1.2 years

First QC Date

September 28, 2023

Last Update Submit

October 15, 2023

Conditions

Exercise Performance

Keywords

ProbioticsIntestinal floraExercise Performance

Outcome Measures

Primary Outcomes (5)

Compare the enhancing endurance performance in sports.
The Isometric Mid-Thigh Pull (IMTP) is a reliable and valid test that can be used to measure maximal force using a custom-made IMTP test device and a force plate. The measured parameters are Peak Force ( the maximum value of force)
before、Week6
Wingate Anaerobic test
Use an anaerobic power bicycle and sprint at full speed for 30 seconds. The measured parameters are Peak power (peak power output, which is the output during the test).
before、Week 3、Week6
Compare muscle gain and fat loss.
Use body fat meter to measure body composition.
before、Week 0、Week 2、Week4、Week6
Compare the enhancing explosive power performance in sports.
Using a force plate and an infrared high-speed camera, a light ball was installed on the subject, and the subject was asked to jump three times at their maximum ability. The maximum jumping force is calculated based on the distance of optical capture displacement.
before、Week 3、Week6
Changes in maximal oxygen uptake(VO2 max)
When the heart rate reaches 170 beats per minute, start collecting gas until exhaustion. The collected gas is used to calculate VO2max through a gas analyzer. The standard for judging exercise exhaustion is that two of the following three conditions are met: (A) The heart rate reaches the maximum heart rate (maximum heart rate = 220 - age). (B) The subject's respiratory exchange rate reaches 1.1. (C) The subject's self-motivated expression of exercise is above 18.
before、Week6

Secondary Outcomes (4)

Changes in sleep quality
Week0、Week3、Week6
Changes in stool form.
Before、Week 6
Changes in immune Index (pg/ml).
before the exhaustive exercise and 3 hours、24hours、48hours after the exhaustive exercise.
Changes in immune Index (pg/ml).
Before、Week 6