Exploration of the Role of Vision on Spatial Cognition

NCT06088797 | Recruiting

• 1 other identifier: 69HCL23_0361
• Study Type: observational
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

Atypical developpement of spatial cognition has been shown in congenital bindness with some consequences on mathematic learning (Cattaneo et al., 2010) as well as on the mental representation of spatial maps (Thinus-Blanc \& Gaunet, 1997). This raises the issue of the role of vision in spatial abilities underlying mathematics and locomotion. These difficulties could also be found in case of partial visual deficiency, like very low visual acuity or large peripheral shrinkage of the visual field.

Conditions

Visual Deficiencies

Keywords

spatial cognition; arithmetic; visual deficiency; blind

Outcome Measures

Primary Outcomes (1)

• percentage of correct responses

  The experimental tasks assess allocentric spatial representations in different modalities with correct responses to spatial vs non spatial questions for the Elementary Spatial Perception test and the mental imagery test.

  through study completion, an average of 2 year

Study Arms (4)

healthy subjects

First time :WISC V 40 minutes Second time :Completion of the 4 experimental tasks 105 minutes

Other: METRIC COMPARISON Tasks : Tactile PVSE test; Other: METRIC COMPARISON Tasks : Classic PVSE test; Other: Mental imagery task; Other: Proprioceptive spatial representation tasks; Other: Tasks assessing number sense based on relative positions or lengths; Other: WISC V Similarity and Span Test; Other: WISC V Arithmetic subtest

blind

First time :WISC V 40 minutes Second time :Completion of the 4 experimental tasks 105 minutes

Other: METRIC COMPARISON Tasks : Tactile PVSE test; Other: Mental imagery task; Other: Proprioceptive spatial representation tasks; Other: Tasks assessing number sense based on relative positions or lengths; Other: WISC V Similarity and Span Test; Other: WISC V Arithmetic subtest

low visual acuity

First time :WISC V 40 minutes Second time :Completion of the 4 experimental tasks 105 minutes

Other: METRIC COMPARISON Tasks : Tactile PVSE test; Other: METRIC COMPARISON Tasks : Classic PVSE test; Other: Mental imagery task; Other: Proprioceptive spatial representation tasks; Other: Tasks assessing number sense based on relative positions or lengths; Other: WISC V Similarity and Span Test; Other: WISC V Arithmetic subtest

reduced visual field

First time :WISC V 40 minutes Second time :Completion of the 4 experimental tasks 105 minutes

Other: METRIC COMPARISON Tasks : Tactile PVSE test; Other: METRIC COMPARISON Tasks : Classic PVSE test; Other: Mental imagery task; Other: Proprioceptive spatial representation tasks; Other: Tasks assessing number sense based on relative positions or lengths; Other: WISC V Similarity and Span Test; Other: WISC V Arithmetic subtest

Interventions

METRIC COMPARISON Tasks : Tactile PVSE test OTHER

Tactile PVSE test The tests are presented in 6 independent booklets, each of which tests a distinct skill: comparison of lengths, comparison of sizes, comparison of obliques, perception of environments, comparison of relative positions in relation to a frame and comparison of relative positions with distractors. The assessment sheet presented in a table with the expected answers will allow you to note whether the answers are correct (rating 1) or not (rating 0). A total of the correct answers from all the sub-tests will give a total score.

blind; healthy subjects; low visual acuity; reduced visual field

METRIC COMPARISON Tasks : Classic PVSE test OTHER

Classic PVSE test Use of the standardized PVSE test printed on thick white paper in 6 separate booklets each containing a subtest (length, size, oblique, middle, relative position and relative position with distractor) The assessment sheet presented in a table with the expected answers will allow you to note whether the answers are correct (rating 1) or not (rating 0). A total of the correct answers from all the sub-tests will give a total score.

healthy subjects; low visual acuity; reduced visual field

Mental imagery task OTHER

This involves answering questions concerning the position or identity of 2 or 3 objects on the basis of the mental representation of a grid by auditory guidance. Each grid must be constructed mentally with the verbal description of the path and the objects encountered.

blind; healthy subjects; low visual acuity; reduced visual field

Proprioceptive spatial representation tasks OTHER

16 configurations of 3 objects with direct or indirect passive exploration of their relative positions. Each grid is presented 3 times with the following 3 questions to which the subject answers yes or no by forced choice a single measure of the number of correct answers which will be the sum of the correct answers obtained to each of the 3 questions in the direct vs indirect condition

blind; healthy subjects; low visual acuity; reduced visual field

Tasks assessing number sense based on relative positions or lengths OTHER

Pointing exercises on a digital line of 50 cm paper tape: the participant points with his finger to a position on the tape, according to the verbal request of the experimenter Measures the intermanual gap during requests for evaluation of 5 times the wand, subtracting the length of a wand, then dividing this length by 2.

blind; healthy subjects; low visual acuity; reduced visual field

WISC V Similarity and Span Test OTHER

The Wechsler Intelligence Scale for Children - Fifth Edition, Australian Standard (WISC-V) is an individually administered and comprehensive clinical instrument used to assess the general thinking and reasoning skills of children aged six years to 16 years. Test results include a Full-Scale Intelligence Quotient (IQ) score as well as age-equivalent rankings and scores for Verbal Comprehension, Visual Spatial, Fluid Reasoning, Working Memory and Processing Speed composites

blind; healthy subjects; low visual acuity; reduced visual field

WISC V Arithmetic subtest OTHER

The WISC-V is an individually administered, comprehensive clinical instrument for assessing the intelligence of children. The primary and secondary subtests are on a scaled score metric with a mean of 10 and a standard deviation (SD) of 3. These subtest scores range from 1 to19, with scores between 8 and 12 typically considered average.

blind; healthy subjects; low visual acuity; reduced visual field

Eligibility Criteria

• Age: 12 Years - 25 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

participant with Visual Deficiencies monitored in the " Centre Technique Régional pour la Déficience Visuelle" or at the " école spécialisée pour déficients visuels "

You may qualify if:

• For all :
• Aged 12 to 25
• Participant not opposed to the research and parents do not oppose participation in the protocol for minors
• For healthy volunteers (normal sighted):
• \- with typical visual development with correction if needed
• For participant with Visual Deficiencies:
• with congenital blindness
• or low visual acuity (between 1/10 and 3/10)
• or with visual field peripheral shrinkage (angle \<20°).

You may not qualify if:

• General knowledge and working memory skills with a standard score of less than 4
• neurological medical history
• Person deprived of liberty by judicial or administrative decision
• Person subject to a legal protection measure (tutorship, curatorship)

Sponsors & Collaborators

• Hospices Civils de Lyon: lead

Study Sites (1)

Equipe Trajectoire du CRNL : INSERM U1028, CNRS UMR 5292

Lyon, France

RECRUITING

Study Officials

• Laure PISELLA, Dr

  Equipe Trajectoire du CRNL : INSERM U1028, CNRS UMR 5292)

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Laure PISELLA, Dr

CONTACT

04 72 91 34 12; laure.pisella@inserm.fr

Hind DRISSI

CONTACT

hind.drissi@inserm.fr

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: October 5, 2023
• First Posted: October 18, 2023
• Study Start: October 20, 2023
• Primary Completion: February 1, 2026
• Study Completion: February 1, 2026
• Last Updated: March 5, 2024

Record last verified: 2024-03

Locations

FR (1)