Changes in Postural Stability Following THA for OA

NCT06088160 | Recruiting

• 1 other identifier: 123634
• Study Type: observational
• Target: 80
• Locations: 1 country
• Sites: 1

Brief Summary

Total hip arthroplasty (THA) is a common surgery that eases pain, restores functional movement, and improves the overall quality of life in people with severe hip osteoarthritis (OA). Unfortunately, problems with postural stability, commonly known as balance, are still noticed in people even years after the surgery. These postural stability problems typically result in falls. The aim of the proposed study is to investigate how THA surgery affects a person's overall quality of life, both physically and psychologically, in terms of postural stability and balance confidence (self-efficacy) within the first three months after THA for osteoarthritis. This prospective cohort study will focus on people over 60 years old.

Conditions

Osteoarthritis, Hip

Keywords

Postural stability; Total hip arthroplasty; Balance confidence; Osteoarthritis; Fall

Outcome Measures

Primary Outcomes (2)

• The Balance Evaluation Systems Test (BESTest)

  The BESTest is a comprehensive performance-based postural stability assessment tool. The BESTest consists of 36 items that assess each underlying component of the balance systems framework (i.e., static stability, motor systems, functional stability limits, verticality, reactive postural control, anticipatory postural control, dynamic stability, sensory integration, and cognitive influences). Each item is scored from 0 (severe balance impairment) to 3 (no balance impairment). The maximum total score is 108 points with higher scores representing better postural stability.

  Pre-THA, and at 2, 6, and 12 weeks post-THA

• The Activities-specific Balance Confidence (ABC) scale

  The 16-item ABC scale assesses the level of confidence a person has in performing a set of daily activities without losing their balance or feeling unsteady. The ABC scale evaluates balance confidence. Each item is rated on scale of 0% (no confidence) to 100% (complete confidence). The final score is the average of all 16-items. ABC scores can be categorized as follows: less than 50 is a low balance confidence, between 50 and 80 is a moderate balance confidence, and over 80 is a high balance confidence.

  Pre-THA, and at 2, 6, and 12 weeks post-THA

Secondary Outcomes (6)

• The University of California, Los Angeles (UCLA) activity scale

  Pre-THA, and at 2, 6, and 12 weeks post-THA

• The EuroQol-Five Dimensions-Five Levels (EQ-5D-5L)

  Pre-THA, and at 2, 6, and 12 weeks post-THA

• The Harris Hip Score

  Pre-THA, and at 2, 6, and 12 weeks post-THA

• The Western Ontario and McMaster Osteoarthritis Index (WOMAC) questionnaire

  Pre-THA, and at 2, 6, and 12 weeks post-THA

• Preoperative Fall Assessment: History of falls (previous 12 months), circumstances of falls, and injury (major or minor).

  Pre-THA

Study Arms (2)

Direct Anterior

This group will consist of people undergoing elective unilateral THA for OA using the Direct Anterior surgical approach

Procedure: Total Hip Arthroplasty

Direct Lateral

This group will consist of people undergoing elective unilateral THA for OA using the Direct Lateral surgical approach

Procedure: Total Hip Arthroplasty

Interventions

Total Hip Arthroplasty PROCEDURE

Total hip arthroplasty is a common surgical procedure performed in people with advanced hip osteoarthritis

Also known as: Total hip replacement

Direct Anterior; Direct Lateral

Eligibility Criteria

• Age: 60 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

People receiving elective unilateral total hip arthroplasty for osteoarthritis

You may qualify if:

• ≥ 60 years of age, scheduled to receive an elective unilateral THA (DA or DL approach) for OA
• Ambulatory for a minimum of 10 meters with or without a mobility aid but without the assistance of another person
• Able to read, write and speak English
• Able to provide consent

You may not qualify if:

• Bilateral THA
• Underwent THA surgery for a diagnosis other than OA
• Any condition that will prevent participants from completing the study such as having a significant neurological, cardiovascular, musculoskeletal condition as denoted by their physician.

Sponsors & Collaborators

• Western University, Canada: lead

Study Sites (1)

London Health Sciences Centre- University Hospital

London, Ontario, N6A 5A5, Canada

RECRUITING

MeSH Terms

Conditions

Osteoarthritis, Hip; Osteoarthritis

Interventions

Arthroplasty, Replacement, Hip

Condition Hierarchy (Ancestors)

Arthritis; Joint Diseases; Musculoskeletal Diseases; Rheumatic Diseases

Intervention Hierarchy (Ancestors)

Arthroplasty, Replacement; Arthroplasty; Orthopedic Procedures; Surgical Procedures, Operative; Plastic Surgery Procedures; Prosthesis Implantation

Study Officials

• Brent Lanting, MD

  London Health Sciences Centre

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Tony I Adebero, MSc.

CONTACT

519-685-8500; tony.adebero@lhsc.on.ca

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: September 28, 2023
• First Posted: October 18, 2023
• Study Start: December 27, 2023
• Primary Completion: August 1, 2025
• Study Completion: November 1, 2025
• Last Updated: July 20, 2025

Record last verified: 2025-07

Data Sharing

• IPD Sharing: Will not share

Locations

CA (1)