Buprenorphine Induction and Naloxone Distribution Program-Combined With Warm Hand-Off Referral to Continued Treatment

NCT06087991 | Completed

• 1 other identifier: 158724
• Study Type: observational
• Target: 65
• Locations: 1 country
• Sites: 1

Brief Summary

This study is a collaboration between the University of Utah and Castleview Hospital in Price, Utah. Buprenorphine is a medication approved by the FDA to treat Opioid Use Disorder (OUD). Castleview Hospital currently does not prescribe buprenorphine in the emergency department (ED) instead it refers patients to outside addiction treatment facilities. This is a service focused project which the University of Utah will provide mentoring and education to Castleview in implementing an in ED buprenorphine/naloxone distribution program along with referral to continued services. After the program has been implemented, the investigators will evaluate it using quantitative surveys of program participants and qualitative interviews of hospital staff and stakeholders.

Conditions

Opioid Abuse

Outcome Measures

Primary Outcomes (1)

• Patient Focused: Number of patients receiving services.

  Will be the aggregate number of individuals who received ED-initiated buprenorphine.

  24 months

Secondary Outcomes (10)

• Implementation and service quality: Satisfaction with projected service

  24 months.

• Implementation and service quality: Patient satisfaction

  enrollment and 6 months post enrollment

• Substance use diagnosis and treatment

  enrollment and 6 months post enrollment

• Social Connectedness

  enrollment and 6 months post enrollment

• Living Conditions

  enrollment and 6 months post enrollment

Study Arms (2)

Quantitative Interviews

Any Castleview patient who participates in this model will be emailed both the Patient Satisfaction Questionnaire Short Form (PSQ 18) and the Government Performance and Results Act surveys after hospital discharge, six months, and at discharge for buprenorphine.

Behavioral: Implementation of the BINDeR-Tx service model

Qualitative Interviews

Qualitative interviews among providers, stakeholders and community members associated with Castleview Hospital will be conducted after the model has been deployed. The qualitative interviews will come from The Consolidated Framework for Implementation Research (CFIR) which is a validated tool that was developed that was developed to evaluate implementation studies.

Behavioral: Implementation of the BINDeR-Tx service model

Interventions

Implementation of the BINDeR-Tx service model BEHAVIORAL

ED-initiated buprenorphine, discharge with naloxone, and warm-hand off referral for continued treatment for individuals with OUD. This is considered standard treatment at the University of Utah ED. In order to extend these services to rural hospitals this study will be assisting Castleview Hospital to establish a similar program.

Qualitative Interviews; Quantitative Interviews

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

25 qualitative interviews of Castleview providers and stakeholders; 337 Castleview patient participants given buprenorphine and naloxone kits

You may qualify if:

• For qualitative interviews with providers, administrators, stakeholders:
• Must be affiliated with Castleview Hospital as a provider, administrator or stakeholder.
• For the quantitative surveys:
• Must be a Castleview Hospital patient who receives the BINDeR-Tx model.

You may not qualify if:

• For qualitative interviews with providers, administrators, stakeholders:
• Not familiar with the BINDeR-Tx model
• No interaction with the BINDeR-Tx model
• For the quantitative surveys:
• Unable to speak and read English
• Subject is unable to provide contact information

Sponsors & Collaborators

• Jerry Cochran: lead

Study Sites (1)

University of Utah

Salt Lake City, Utah, 84108, United States

Location

Related Publications (1)

• Seliski N, Madsen T, Eley S, Colosimo J, Engar T, Gordon A, Barnett C, Humiston G, Morsillo T, Stolebarger L, Smid MC, Cochran G. Implementation of a rural emergency department-initiated buprenorphine program in the mountain west: a study protocol. Addict Sci Clin Pract. 2024 Sep 3;19(1):63. doi: 10.1186/s13722-024-00496-0.

  PMID: 39228007 DERIVED

MeSH Terms

Conditions

Opioid-Related Disorders

Condition Hierarchy (Ancestors)

Narcotic-Related Disorders; Substance-Related Disorders; Chemically-Induced Disorders; Mental Disorders

Study Officials

• Jerry Cochran

  University of Utah

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Associate Professor

Study Record Dates

• First Submitted: October 11, 2023
• First Posted: October 18, 2023
• Study Start: April 1, 2023
• Primary Completion: October 1, 2024
• Study Completion: October 1, 2024
• Last Updated: June 24, 2025

Record last verified: 2025-06

Locations

US (1)