Urinary Markers by SpectrosCopy: Diagnostic Aid in oncologY - Application to Urological Cancers
MUSCADE
1 other identifier
observational
1,800
1 country
1
Brief Summary
This study aims to evaluate the performance of vibrational spectroscopy (Infrared and Raman spectroscopy techniques) in bladder cancer diagnosis using urine samples.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Mar 2023
Typical duration for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
March 6, 2023
CompletedFirst Submitted
Initial submission to the registry
October 11, 2023
CompletedFirst Posted
Study publicly available on registry
October 17, 2023
CompletedPrimary Completion
Last participant's last visit for primary outcome
March 6, 2025
CompletedStudy Completion
Last participant's last visit for all outcomes
March 6, 2026
CompletedOctober 17, 2023
October 1, 2023
2 years
October 11, 2023
October 11, 2023
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Fourier Transform Infrared Spectroscopy
Analyze urine samples by infrared spectroscopy after drying step and without any further sample preparation. The obtained spectra will be preprocessed and analyzed by multivariate algorithms to discriminate bladder cancer patients from control group.
A 36 months
Secondary Outcomes (1)
Surface-enhanced Raman spectroscopy
A 36 months
Study Arms (2)
Bladder cancer group
Bladder cancer group represents patients attending or hospitalized in Urology department, Reims University Hospital and in whom, tumor is visualized during cystoscopy and confirmed by the histological examination of entire resected lesion after Trans Urethral Resection of Bladder Tumor (TURBT).
Control group
Control group includes patients consulting for cystoscopy examination in Urology department, Reims University Hospital without any tumor visualization during cystoscopy examination.
Interventions
Eligibility Criteria
Patients attending for cystoscopy examination or hospitalized in Urology department, Reims University Hospital.
You may qualify if:
- Must be over 18 years of age
- Able to give consent and understand the purpose the study
- Agree to participate in the study and having signed the non-objection document
- Admitted to a urology consultation for cystoscopy
You may not qualify if:
- Refused to participate in the study or unable to give consent
- without a native bladder
- with a bladder fistula
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- CHU de Reimslead
Study Sites (1)
Damien JOLLY
Reims, France
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- CASE CONTROL
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
October 11, 2023
First Posted
October 17, 2023
Study Start
March 6, 2023
Primary Completion
March 6, 2025
Study Completion
March 6, 2026
Last Updated
October 17, 2023
Record last verified: 2023-10