Rural Illinois Lung Cancer Screening Initiative

NCT06084078 | Recruiting

• 1 other identifier: LDCT Screening
• Study Type: observational
• Target: 10,000
• Locations: 1 country
• Sites: 1

Brief Summary

The role of this observational study is to access the feasibility of providing lung cancer screening using a designated nurse navigator through lung cancer screening clinic. Eligible participants will be identified using medical records, eligibility will be confirmed through phone call, screening visits will be scheduled as in-person visit or telehealth visit. Computed tomography screening will be performed at an approved center closer to the individuals place of living and results will be discussed during follow-up in-person visit or telehealth visit.

Conditions

Lung Cancer

Keywords

cancer screening; LDCT; Lung cancer

Outcome Measures

Primary Outcomes (2)

• Screening rate

  Percentage of individuals screened (completed CT imaging) with and without telehealth

  Through study completion, an average of 1 year

• Early stage diagnosis

  Percentage of individuals diagnosed with lung cancer at an early stage of the disease

  Through study completion, an average of 1 year

Secondary Outcomes (3)

• Time to treatment initiation

  Through study completion, an average of 1 year

• Adherence to Screening

  Through study completion, an average of 1 year

• Cost

  Through study completion, an average of 1 year

Study Arms (2)

Telehealth cohort

Individuals who opt to do the screening using telehealth. Telehealth using video assisted techniques or using telephone.

In-person cohort

Individuals who are willing to travel to the hospital for in-person screening and follow-up

Eligibility Criteria

• Age: 50 Years - 80 Years
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The risk of lung cancer increases with age and smoking status and hence this age range is recommended for receiving lung cancer screening. As per USPSTF criteria our screening initiative will include individuals 50-80 years, subjects of all sex/gender and all race/ethnic groups. Screening eligible individuals included in our pilot study consisted of 54.4 % women, 75% of non-Hispanic whites, 24% non-Hispanic blacks and 1.2% belonged to 'other' race category. Non-Hispanic black individuals with smoking history have a higher risk of developing lung cancer than a non-Hispanic white. Very few Hispanic persons and women tend to accumulate fewer pack-years over a long period of time.

You may qualify if:

• All individuals 50-80 years of age
• pack-year smoking history
• Currently smoke or have quit within the past 15 years:

You may not qualify if:

• Individuals 49 years and below or 81 years and above
• Has not smoked in 15 or more years
• Individuals who develop a health problem that makes them unwilling or unable to have surgery if lung cancer is detected.

Sponsors & Collaborators

• Southern Illinois University: lead

Study Sites (1)

Sowmy Thuppal

Springfield, Illinois, 62704, United States

RECRUITING

Related Publications (2)

• Thuppal S, Hendren JR, Colle J, Sapra A, Bhandari P, Rahman R, Krus-Johnston A, Hoffman MR, Foray N, Hazelrigg S, Crabtree T. Proactive Recruitment Strategy for Patient Identification for Lung Cancer Screening. Ann Fam Med. 2023 Mar-Apr;21(2):119-124. doi: 10.1370/afm.2905.

  PMID: 36973046 RESULT

• National Lung Screening Trial Research Team; Aberle DR, Adams AM, Berg CD, Black WC, Clapp JD, Fagerstrom RM, Gareen IF, Gatsonis C, Marcus PM, Sicks JD. Reduced lung-cancer mortality with low-dose computed tomographic screening. N Engl J Med. 2011 Aug 4;365(5):395-409. doi: 10.1056/NEJMoa1102873. Epub 2011 Jun 29.

  PMID: 21714641 RESULT

MeSH Terms

Conditions

Lung Neoplasms

Condition Hierarchy (Ancestors)

Respiratory Tract Neoplasms; Thoracic Neoplasms; Neoplasms by Site; Neoplasms; Lung Diseases; Respiratory Tract Diseases

Study Officials

• Sowmy Thuppal, MD PhD

  Southrn Illinois University School of Medicine

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Sowmy Thuppal, MD PhD

CONTACT

217-545-2320; sthuppal83@siumed.edu

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 30 Years
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: September 27, 2023
• First Posted: October 16, 2023
• Study Start: September 1, 2024
• Primary Completion (Estimated): August 31, 2029
• Study Completion (Estimated): August 31, 2030
• Last Updated: April 24, 2026

Record last verified: 2025-04

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)