Impact of the CRRT Management Protocol on Prognostic Outcome in Patients With Septic Acute Kidney Injury

NCT06083285 | Completed

• 1 other identifier: XMaimaitirexiati
• Study Type: observational
• Target: 76
• Locations: 1 country
• Sites: 1

Brief Summary

The implementation of CRRT nursing team management program in the treatment of SAKI can significantly reduce the incidence of adverse events and complications in CRRT nursing, which has a positive role in improving the success rate of CRRT treatment and the clinical outcome of patients.

Conditions

To Explore the Influence of CRRT Nursing Team Management Plan on the Prognosis of SAKI Patients

Outcome Measures

Primary Outcomes (1)

• To explore the influence of CRRT nursing team management plan on the prognosis of SAKI patients.

  The incidence of unplanned removal of CRRT, unplanned extubation and CRRT nursing related complications in the observation group were lower than those in the control group (P \<0.05). Kaplan Meier survival curve showed that the survival rate of patients in the observation group was higher than that in the control group (P \<0.05).

  3-10 days

Study Arms (2)

Control group

Observation group

Other: Implement the CRRT specialist nursing group management program on the basis of routine care

Interventions

Implement the CRRT specialist nursing group management program on the basis of routine care OTHER

Training the department nurses on CRRT related theoretical knowledge and operation skills; guiding the process of CRRT different treatment modes, solving CRRT nursing problems, evidence-based nursing guidance; consulting CRRT treatment and nursing related treatment, timely understanding the new progress; responsible for CRRT nursing quality control, etc.

Observation group

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

36 SAKI patients who were treated with CRRT in ICU of our hospital from February 2021 to August 2021 were set as the control group, and the routine bedside CRRT nursing management process was implemented in this stage; In addition, from September 2021 to March 2022, 40 SAKI patients who received CRRT treatment in our ICU were set as the observation group.The management plan of CRRT special nursing team was implemented to compare the incidence of non planned removal of CRRT, unplanned extubation and CRRT nursing related complications between the two groups, as well as the difference of coagulation function indexes before and 3 days after nursing.

You may qualify if:

• The Guidelines for Emergency Treatment of Sepsis / Septic Shock in China (2018)\[4\]Diagnostic criteria for moderate sepsis; ② meets the Organization for Improving Global Kidney Disease Outcomes (KDIGO) Clinical Practice Guidelines: AKI\[5\]Relevant diagnostic criteria in; ③ received CRRT as indicated for CRRT; ④ in ICU for longer than 24 hours; ⑤ signed consent.

You may not qualify if:

• with chronic organ failure, or advanced malignancy; ② with previous history of chronic kidney disease, retrorenal urinary tract obstruction; ③ with incomplete clinical data.

Sponsors & Collaborators

• Xinjiang Medical University: lead

Study Sites (1)

Xinjiang Medical University of Affiliated tumour Hospital

Ürümqi, Xinjiang, 830011, China

Location

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Chief Physician

Study Record Dates

• First Submitted: October 8, 2023
• First Posted: October 13, 2023
• Study Start: February 1, 2021
• Primary Completion: May 1, 2023
• Study Completion: June 7, 2023
• Last Updated: October 13, 2023

Record last verified: 2023-10

Locations

CN (1)