NCT06077318

Brief Summary

Parastomal hernia (PSH) is difficult to manage, with high rates of post-operative recurrence and complication. Keyhole and Sugarbaker are the most commonly used techniques in the surgical repair of the PSH. However, the efficacy and safety of the two surgical methods have not been adequately compared in the East Asian population. Patients diagnosed with PSH who underwent Sugarbaker or Keyhole repair from August 2012 to August 2022 will be included. Patient demographic data and postoperative outcomes will be retrospectively analyzed. The primary outcome measure is the recurrence rate at one year follow-up time.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
100

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Oct 2023

Shorter than P25 for all trials

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

September 19, 2023

Completed
22 days until next milestone

First Posted

Study publicly available on registry

October 11, 2023

Completed
9 days until next milestone

Study Start

First participant enrolled

October 20, 2023

Completed
Same day until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 20, 2023

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 20, 2023

Completed
Last Updated

October 11, 2023

Status Verified

October 1, 2023

Enrollment Period

Same day

First QC Date

September 19, 2023

Last Update Submit

October 8, 2023

Conditions

Keywords

Parastomal herniaKeyholeSugarbakermesh

Outcome Measures

Primary Outcomes (1)

  • recurrence rate

    recurrence was determined by CT scan

    one year follow-up time

Secondary Outcomes (4)

  • surgical site infection

    30 days after surgery

  • reoperation and readmission

    30 days after surgery

  • chronic pain

    one year follow-up time

  • major complication

    one year follow-up time

Study Arms (2)

Keyhole repair

The keyhole technique involves placing a mesh with a slit in the central hole around the intestinal ring, allowing facilitating the passage of the intestine through the central slit.

Other: Keyhole repair

Sugarbaker repair

The modified Sugarbaker technique uses a mesh to place a patch on the lateralized intestine, effectively preventing herniation of abdominal contents through the stoma.

Other: Sugarbaker repair

Interventions

The keyhole technique involves placing a mesh with a slit in the central hole around the intestinal ring, allowing facilitating the passage of the intestine through the central slit.

Keyhole repair

The modified Sugarbaker technique uses a mesh to place a patch on the lateralized intestine, effectively preventing herniation of abdominal contents through the stoma.

Sugarbaker repair

Eligibility Criteria

Sexall
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients diagnosed with PSH who underwent Sugarbaker or Keyhole repair from August 2012 to August 2022 were included.

You may qualify if:

  • Only PSH patients who received intraperitoneal onlay Sugarbaker and Keyhole mesh were included.

You may not qualify if:

  • Patients with less than one year follow-up periods were excluded from the cohort.
  • Patients received other repair approaches.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (1)

  • Shi H, Li S, Lin Y, Yang D, Dong W, Song Z, Song H, Gu Y. Comparison of the 3-D mesh and Sugarbaker repair for parastomal hernia: a single center experience in China. Updates Surg. 2024 Sep;76(5):1991-1996. doi: 10.1007/s13304-024-01946-9. Epub 2024 Jul 21.

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Director

Study Record Dates

First Submitted

September 19, 2023

First Posted

October 11, 2023

Study Start

October 20, 2023

Primary Completion

October 20, 2023

Study Completion

December 20, 2023

Last Updated

October 11, 2023

Record last verified: 2023-10