NCT06076798

Brief Summary

AFGen1 is indicated for use on symptomatic or asymptomatic adults who are at risk of developing or who have atrial fibrillation, where a software assisted analysis of ambulatory ECG is needed to identify episodes of Afib. The purpose of this study is to establish the clinical performance of AFGen1 on human participants.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
15

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Oct 2023

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

October 4, 2023

Completed
1 day until next milestone

Study Start

First participant enrolled

October 5, 2023

Completed
6 days until next milestone

First Posted

Study publicly available on registry

October 11, 2023

Completed
25 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 5, 2023

Completed
19 days until next milestone

Study Completion

Last participant's last visit for all outcomes

November 24, 2023

Completed
Last Updated

April 11, 2024

Status Verified

April 1, 2024

Enrollment Period

1 month

First QC Date

October 4, 2023

Last Update Submit

April 10, 2024

Conditions

Keywords

ECG signal quality

Outcome Measures

Primary Outcomes (2)

  • Quantitative Evaluation

    For the quantitative evaluation of the mean and standard deviation of the QRS amplitude, duration, and timing correlations for all study subjects and for the end of the wear period for those relevant subjects, the mean correlation coefficient must be greater than 0.95 and standard deviation must be less than 0.05 to validate a 95% confidence interval with significant factor of assurance. validate a 95% confidence interval with significant factor of assurance.

    7 days

  • Adhesive performance

    For the adhesive performance element of the study, the overall average wear time for the device must be greater than 5-days.

    7 days

Study Arms (1)

Wear AFGen1

Wear AFGen1 for 7 days. ECG co-measurement with 12 lead device at start and end of wear period

Device: ECG co-measurement

Interventions

Measure ECG with 12 lead device at same time that AFGen1 is monitoring ECG

Wear AFGen1

Eligibility Criteria

Age18 Years - 90 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

The study shall involve 15 participants (approximately equal number of males and females, meeting inclusion and exclusion criteria.

You may qualify if:

  • \. 18+ willing to sign the consent form

You may not qualify if:

  • Implanted pacemakers
  • Implanted cardioverter defibrillators
  • Implanted cardiac resynchronization devices
  • Potential life-threatening arrythmias
  • Physical or mental health conditions that would prevent the person from being able to follow instructions regarding participation in the study
  • Open wounds, abraded or irritated skin at the application site
  • Planned to undergo a MRI during the course of the study duration
  • Known or suspected to be pregnant
  • Student or employee of TriVirum

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

4927 Lillian Street

San Diego, California, 92110, United States

Location

MeSH Terms

Conditions

Atrial Fibrillation

Condition Hierarchy (Ancestors)

Arrhythmias, CardiacHeart DiseasesCardiovascular DiseasesPathologic ProcessesPathological Conditions, Signs and Symptoms

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 4, 2023

First Posted

October 11, 2023

Study Start

October 5, 2023

Primary Completion

November 5, 2023

Study Completion

November 24, 2023

Last Updated

April 11, 2024

Record last verified: 2024-04

Data Sharing

IPD Sharing
Will not share

Locations