NCT06075420

Brief Summary

The objective of study is to evaluate the efficacy and safety of short duration of DAPT after GENOSS® DES Implantation in patients with coronary artery disease.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,000

participants targeted

Target at P75+ for all trials

Timeline
21mo left

Started Aug 2021

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress74%
Aug 2021Dec 2027

Study Start

First participant enrolled

August 18, 2021

Completed
2.1 years until next milestone

First Submitted

Initial submission to the registry

October 4, 2023

Completed
6 days until next milestone

First Posted

Study publicly available on registry

October 10, 2023

Completed
4.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2027

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2027

Last Updated

February 21, 2025

Status Verified

February 1, 2025

Enrollment Period

6.4 years

First QC Date

October 4, 2023

Last Update Submit

February 18, 2025

Conditions

Outcome Measures

Primary Outcomes (1)

  • Device-oriented composite endpoint

    DOCE is defined as a composite of cardiac death, target vessel-related myocardial infarction (TV-MI) and clinically indicated target-lesion revascularization (TLR).

    at 12 months after the procedure

Secondary Outcomes (11)

  • Patient-oriented composite endpoint

    at 12 months after the procedure

  • All-cause deaths

    at 12 months after the procedure

  • Cardiac death

    at 12 months after the procedure

  • Non-cardiac death

    at 12 months after the procedure

  • Any myocardial infarction

    at 12 months after the procedure

  • +6 more secondary outcomes

Study Arms (1)

GENOSS Sirolimus Eluting Coronary Stent System

Patients with coronary artery disease treated with the GENOSS DES

Eligibility Criteria

Age19 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients with coronary artery disease treated with GENOSS DES

You may qualify if:

  • Patients of 19 and over
  • Patients with coronary artery disease treated with GENOSS SES
  • Participants who voluntarily decide to participate in this clinical trial, agree to the study protocol and clinical follow-up plan, and provide written informed consent as study participants

You may not qualify if:

  • Patients with cardiogenic shock at the time of hospitalization
  • Patients who are pregnant or planning to become pregnant
  • Patients with a life expectancy of less than 1 year
  • Patients participating in randomized controlled trials using other medical devices
  • Patients who have already received treatment with another DES (Drug Eluting Stent) or BMS (Bare Metal Stent) at the time of registration (However, other stent insertions are allowed due to failure of GENOSS DES insertion)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Wonju Severance Christian Hospital

Wŏnju, Gangwon State, South Korea

RECRUITING

Central Study Contacts

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Target Duration
12 Months
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 4, 2023

First Posted

October 10, 2023

Study Start

August 18, 2021

Primary Completion (Estimated)

December 31, 2027

Study Completion (Estimated)

December 31, 2027

Last Updated

February 21, 2025

Record last verified: 2025-02

Data Sharing

IPD Sharing
Will not share

Locations