Efficacy of Korean Manupuncture on Pain in Women With Endometriosis: a Parallel-group Randomized Controlled Trial

NCT06073379 | Completed

• 1 other identifier: POUHIN AOIparaM 2021
• Study Type: interventional
• Target: 74
• Locations: 1 country
• Sites: 1

Brief Summary

Endometriosis is defined as the presence and development of hormone-dependent endometrial tissue comprising both glands and stroma outside the endometrium and myometrium. It affects 10-15% of women of childbearing age; of these, 25% are diagnosed following a consultation for infertility, and 25% following a consultation for pelvic pain. This disease has a strong functional (pain and infertility) and organic impact, its numerous symptoms can have a considerable effect on quality of life. Individualized analgesic management with multidisciplinary care (medical, surgical and psychological) can improve quality of life for women with endometriosis, but current treatment remains insufficient. Korean manupuncture is a complementary treatment technique that does not interact with current treatments. It's a holistic discipline that draws up a highly detailed map of the body's correspondence on the hand. Each body zone corresponds to a zone on the hand. The aim of this research is to evaluate the effect of Korean manupuncture on endometriosis-related pain. Patients will be randomly assigned to 2 groups, 30 to the "Korean manupuncture" group and 30 to the "placebo/control" group. Patients will be blinded to their assigned group.

Conditions

Endometriosis; Pain

Outcome Measures

Primary Outcomes (1)

• Variation in the Visual Analog Scale (VAS)

  Between Day 1 and Day 29

Study Arms (2)

Korean manupuncture

EXPERIMENTAL

Other: Korean manupuncture

Placebo/control

PLACEBO COMPARATOR

Other: Placebo session

Interventions

Korean manupuncture OTHER

Energy assessment on hands and body Correspondence point technique on hands Energy rebalancing with ki Maeks on hands Moxa technique on hands

Korean manupuncture

Placebo session OTHER

Energy assessment on hands and body Correspondence point technique on the hands Energy rebalancing with ki Maeks on hands (use of Qi bong) Moxa technique on hands (placebo moxas)

Placebo/control

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Person having given oral consent
• Woman of legal age
• Woman diagnosed with endometriosis consulting for pain management

You may not qualify if:

• Not affiliated to the national health insurance system
• Person under legal protection (curatorship, guardianship)
• Person under court order
• Pregnant or breast-feeding women
• Menopausal women (menopause is defined as amenorrhea lasting more than 12 consecutive months)
• An adult unable to give consent
• Women who have had a hysterectomy
• Women who cannot speak or read French
• Hands not accessible for treatment
• Inability to follow the entire protocol
• Cognitive impairment

Sponsors & Collaborators

• Centre Hospitalier Universitaire Dijon: lead

Study Sites (1)

Chu Dijon Bourgogne

Dijon, France

Location

MeSH Terms

Conditions

Endometriosis; Pain

Condition Hierarchy (Ancestors)

Genital Diseases, Female; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Genital Diseases; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: SUPPORTIVE CARE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: September 29, 2023
• First Posted: October 10, 2023
• Study Start: November 29, 2023
• Primary Completion: July 9, 2025
• Study Completion: July 9, 2025
• Last Updated: February 9, 2026

Record last verified: 2026-02

Locations

FR (1)