NCT06070727

Brief Summary

Prosthetic rehabilitation of acquired maxillary defects represents a challenging mission for both the prosthodontist and psychologically traumatized patients. These defects may be due to trauma, pathological conditions, or surgical resection of oral tumors. The resulting main problem is oronasal communication leading to impairment in mastication, swallowing, speech, and facial esthetics

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
20

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Jul 2023

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 4, 2023

Completed
3 months until next milestone

First Submitted

Initial submission to the registry

September 20, 2023

Completed
16 days until next milestone

First Posted

Study publicly available on registry

October 6, 2023

Completed
9 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 4, 2024

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

August 4, 2024

Completed
Last Updated

October 6, 2023

Status Verified

July 1, 2023

Enrollment Period

1 year

First QC Date

September 20, 2023

Last Update Submit

October 1, 2023

Conditions

Keywords

Polyetherketoneketone, Metal, Obturator

Outcome Measures

Primary Outcomes (1)

  • Patient satisfaction

    Obturator functioning scale (OFS) used for evaluation of patient satisfaction, such as improvement in speech, better swallowing with the obturator, feeling and appearance of the upper lip, general feeling in the mouth, self confidence, and avoidance of social family events

    6 months

Study Arms (2)

Metal framework group

OTHER

group A: Patients will receive metallic framework with obturator for 6 months, then the metallic obturator will be replaced by PEKK obturator for another 6 months.

Other: Obturator

PEKK framework group

OTHER

Group B: Patients will receive PEKK obturator for 6 months, then the same patients will receive metallic framework obturator for another 6 months.

Other: Obturator

Interventions

Evaluation of patient satisfaction and oral healthy related quality of life of Polyetherketoneketone(PEKK) and metal framework for management of maxillectomy cases.

Metal framework groupPEKK framework group

Eligibility Criteria

Age30 Years - 70 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • The patient will be selected according to the following criteria:
  • Patient with unilateral total maxillectomy.
  • Patients will have sufficient number of remaining teeth.
  • Free from any signs of inflammation in defect area.
  • Patient 3 years after receiving radiation.
  • The defect size is small or large.
  • Patient with susceptibility of recurrence.

You may not qualify if:

  • Patient is still receiving radiation.
  • Defect result from trauma.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Mohammed ELSawy

Al Mansurah, 12345, Egypt

Location

MeSH Terms

Conditions

Patient Satisfaction

Condition Hierarchy (Ancestors)

Treatment Adherence and ComplianceHealth BehaviorBehavior

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
TREATMENT
Intervention Model
CROSSOVER
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 20, 2023

First Posted

October 6, 2023

Study Start

July 4, 2023

Primary Completion

July 4, 2024

Study Completion

August 4, 2024

Last Updated

October 6, 2023

Record last verified: 2023-07

Data Sharing

IPD Sharing
Will not share

Locations