Prognostic Understanding in ESC (ProgESC Study)

NCT06067087 | Completed

• 2 other identifiers: EDGE 158645IRAS 328196
• Study Type: observational
• Target: 91
• Locations: 1 country
• Sites: 1

Brief Summary

This study aims to assess how aware patients with advanced cancer are about their prognosis when they are referred to an Enhanced Supportive Care (ESC) service. Further, the study aim to assess the relationship between patients prognostic understanding and their mental health, quality of life, trust in medical professionals as well as their perception of the care they receive. The study will involve adult patients with advanced cancer who are referred to the ESC service at London University College Hospital. Patients who agree to participate will provide consent and answer a questionnaire. The questionnaire will cover their prognostic awareness, psychological symptoms, and quality of life. It takes about 20 minutes to complete and can be done online via RedCap

Conditions

Advanced Cancer

Keywords

Prognostic understanding; Enhanced Supportive Care Team; Quality of life; Anxiety; Depression; Satisfaction

Outcome Measures

Primary Outcomes (1)

• Patients' prognostic understanding

  Patients' prognostic understanding about their illness assessed through the Prognosis and Treatment Perception Questionnaire. This questionnaire assesses patient beliefs regarding the likelihood of cure, the preference for receiving prognostic information as well as the perceived helpfulness of knowing about prognosis

  within 1 week after patient assessment by the Enhanced Supportive Care Team

Secondary Outcomes (1)

• Perceived value of prognostic information

  within 1 week after patient assessment by the Enhanced Supportive Care Team

Other Outcomes (5)

• Symptoms of anxiety

  within 1 week after patient assessment by the Enhanced Supportive Care Team

• Symptoms of depression

  within 1 week after patient assessment by the Enhanced Supportive Care Team

• Patients' quality of life

  within 1 week after patient assessment by the Enhanced Supportive Care Team

Study Arms (1)

Patients with advanced cancer

Patients with advanced cancer that are referred to the Enhanced Supportive Care Team at University College London Hospital

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Population: Consecutive patients with advanced cancer being referred to the Enhanced Supportive Care Team Setting: UCH Macmillan Cancer Centre

You may qualify if:

• All participants aged 18 and older with advanced cancer referred to the ESC team will be eligible for this study.

You may not qualify if:

• Younger than 18 years
• Insufficient English language to complete questionnaires
• cognitive impairment
• Participants who, in the opinion of the member of the ESC team, would not be appropriate to participate

Sponsors & Collaborators

• University College, London: lead

Study Sites (1)

University College Hospital Macmillan Cancer Centre

London, United Kingdom

Location

Related Publications (28)

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MeSH Terms

Conditions

Anxiety Disorders; Depression; Personal Satisfaction

Condition Hierarchy (Ancestors)

Mental Disorders; Behavioral Symptoms; Behavior

Study Officials

• Patrick Stone, Prof

  University College, London

  PRINCIPAL INVESTIGATOR

• Joanna Sheppard, MD

  University College London Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: September 27, 2023
• First Posted: October 4, 2023
• Study Start: November 15, 2023
• Primary Completion: August 31, 2024
• Study Completion: August 31, 2024
• Last Updated: January 3, 2025

Record last verified: 2025-01

Locations

GB (1)