NCT06056271

Brief Summary

Observational, multi-center, clinical device registry for US patients with a primary goal to observe the clinical outcomes in patients who are mapped with Volta Medical's VX1 or AF-Xplorer systems during AF ablation procedures.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
400

participants targeted

Target at P75+ for all trials

Timeline
19mo left

Started Mar 2024

Typical duration for all trials

Geographic Reach
1 country

4 active sites

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress58%
Mar 2024Dec 2027

First Submitted

Initial submission to the registry

September 20, 2023

Completed
8 days until next milestone

First Posted

Study publicly available on registry

September 28, 2023

Completed
6 months until next milestone

Study Start

First participant enrolled

March 19, 2024

Completed
3.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2027

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2027

Last Updated

December 10, 2025

Status Verified

December 1, 2025

Enrollment Period

3.7 years

First QC Date

September 20, 2023

Last Update Submit

December 2, 2025

Conditions

Outcome Measures

Primary Outcomes (1)

  • Primary Clinical Efficacy Outcome

    Percentage of subjects free from clinically significant AF or atrial arrhythmia recurrences, after one or multiple ablation procedures, stratified by type of clinical workflow and ablation history.

    12 and 24 months

Interventions

Percutaneous, catheter-based ablation of atrial fibrillation

Eligibility Criteria

Age21 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Adult patients indicated for ablation for atrial fibrillation

You may qualify if:

  • Patients 21 years of age or older who is:
  • indicated for AF ablation or
  • Who has received an AF-ablation with the past 24 months where VX1 was used or
  • Patients are receiving or received a catheter ablation procedure for AF according to current guidelines
  • Patients must be able and willing to provide written informed consent to participate in the clinical trial

You may not qualify if:

  • Patients not indicated or were not indicated for catheter ablation according to current guidelines
  • Patients with AF secondary to an obvious reversible cause
  • Patients who are or may potentially be pregnant
  • Enrollment in an investigational study evaluating another non-VX1 investigational device, biologic, or drug

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (4)

Endeavor Health

Evanston, Illinois, 60201, United States

RECRUITING

Kansas City Cardiac Arrhythmia Research LLC

Overland Park, Kansas, 66211, United States

RECRUITING

Northwell Health

New York, New York, 10075, United States

RECRUITING

Ohio State University

Columbus, Ohio, 43210, United States

RECRUITING

MeSH Terms

Conditions

Atrial Fibrillation

Condition Hierarchy (Ancestors)

Arrhythmias, CardiacHeart DiseasesCardiovascular DiseasesPathologic ProcessesPathological Conditions, Signs and Symptoms

Central Study Contacts

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 20, 2023

First Posted

September 28, 2023

Study Start

March 19, 2024

Primary Completion (Estimated)

December 1, 2027

Study Completion (Estimated)

December 1, 2027

Last Updated

December 10, 2025

Record last verified: 2025-12

Data Sharing

IPD Sharing
Will not share

Locations