NCT06047340

Brief Summary

This study will test G:DATA, a simple computer game designed to diagnose Alzheimer's Disease, in three different groups of people, some of whom have Alzheimer's Disease. It will look at whether the results of G:DATA match the results of tests that are used to diagnose people with Alzheimer's Disease now. The Investigators will also ask patients and healthcare staff for participant views on the G:DATA game.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
30

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Oct 2023

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

September 2, 2023

Completed
19 days until next milestone

First Posted

Study publicly available on registry

September 21, 2023

Completed
11 days until next milestone

Study Start

First participant enrolled

October 2, 2023

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2023

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2023

Completed
Last Updated

September 21, 2023

Status Verified

September 1, 2023

Enrollment Period

3 months

First QC Date

September 2, 2023

Last Update Submit

September 19, 2023

Conditions

Outcome Measures

Primary Outcomes (1)

  • In Game Navigation Test Score

    In Game Navigational Test Score of each participant in correlation to clinical assessment score. This doesn't use any form of scale and higher scores refer to worse outcome.

    9 months

Study Arms (3)

Early AD

EXPERIMENTAL

10 participants with early AD Intervention: Game

Device: G:DATA, dementia screen videogame

MCI

EXPERIMENTAL

10 participants with mild cognitive impairment Intervention: Game

Device: G:DATA, dementia screen videogame

Health Control

ACTIVE COMPARATOR

10 healthy control participants Intervention: Game

Device: G:DATA, dementia screen videogame

Interventions

A videogame for screening

Early ADHealth ControlMCI

Eligibility Criteria

Age55 Years - 79 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Aged between 55-79 years
  • Willing and able to provide informed consen-

You may not qualify if:

  • A concurrent diagnosis of epilepsy
  • A history of severe visual impairment, e.g. macular degeneration, diabetic reti-nopathy, as determined by the clinical team
  • A history of head trauma
  • Presence of Sleep Apnoea
  • History of alcohol dependence
  • History of illicit drug use
  • Severe upper limb arthropathy
  • The use of cognitive enhancing drugs e.g. cholinesterase inhibitors-

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Hywel Dda University Health Board

Carmarthen, Wales, SA31 3BB, United Kingdom

Location

MeSH Terms

Conditions

Alzheimer Disease

Condition Hierarchy (Ancestors)

DementiaBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesTauopathiesNeurodegenerative DiseasesNeurocognitive DisordersMental Disorders

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
SCREENING
Intervention Model
PARALLEL
Model Details: Interventional study with three study arms (mild cognitive impairment, mild AD-related dementia, healthy controls).
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 2, 2023

First Posted

September 21, 2023

Study Start

October 2, 2023

Primary Completion

December 31, 2023

Study Completion

December 31, 2023

Last Updated

September 21, 2023

Record last verified: 2023-09

Data Sharing

IPD Sharing
Will share

Participants will be assigned a unique study ID and data collected will be labelled with the study ID only. An enrolment log will record participant name, date of birth and hospital or NHS number. No personal identifiable information will be included as part of the research dataset leaving the local site for analysis.

Shared Documents
STUDY PROTOCOL
Time Frame
start date 01/09/23 end date 31/12/23 I couldn't select the no ipd sharing option
Access Criteria
no one beyond the study team will be able to access data I couldn't select the no ipd sharing option
More information

Locations