An App-based Instructional Platform to Improve Eye Drop Recall

NCT06045390 | Completed

• 1 other identifier: 23-39908
• Study Type: interventional
• Target: 20
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this interventional study is to assess whether an in-office, language-concordant instructional app improves drop regimen recall in a population of glaucoma patients who are on multi-drop regimens. Participants will be divided into two groups -- those who use the app and those who do not. The app will have narrated information regarding the drop regimen, a quiz to test understanding of the regimen, and will enable a graphical printout of the eye drops and schedule. At one month, both groups will be assessed on their eye drop regimen recall.

Conditions

Glaucoma

Outcome Measures

Primary Outcomes (1)

• Percentage accuracy of drop regimen recall

  This will be assessed through questions querying which drops the patients are taking, the number of times they are taking each drop, and the laterality of each drop. Each answer/drop will be individual recorded, and then total number of correct answers will be divided by the total number of questions.

  1 month follow up from time of intervention

Secondary Outcomes (1)

• Overall medication adherence, assessed through the modified Morisky Adherence Scale, a widely published scale for general medication adherence

  1 month follow up from time of intervention

Study Arms (2)

App arm

EXPERIMENTAL

The intervention is an in-office app that contains graphical and narrated information on a patient's specific drop regimen, and includes a quiz and a graphical print-out of their drop schedule. The patient will use the app during their clinic visit.

Other: App

Standard arm

NO INTERVENTION

The standard arm will be the standard of care, which involves a provider explanation of their drop regimen (using a phone interpreter if needed).

Interventions

App OTHER

App features (App will be used during the office visit): * Pictorial representation of drops (color-coded) and schedule. * Quiz to assess understanding of the regimen. * Narrated instructions (language-concordant) on how and when (frequency and eye laterality) to take each drop. * Graphical print-out of the regimen.

Also known as: App-based drop instructions

App arm

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• patients with a diagnosis of glaucoma (any type)
• drop regimen of at least 2 pressure-lowering drops
• languages supported at this time: English, Spanish, Cantonese

You may not qualify if:

• concurrent eye conditions necessitating additional eye drops
• inability to self-administer eye drops
• inability to engage with app (either visual or other barrier)

Sponsors & Collaborators

• University of California, San Francisco: lead

Study Sites (1)

San Francisco General Hospital

San Francisco, California, 94110, United States

Location

Related Publications (3)

• Newman-Casey PA, Blachley T, Lee PP, Heisler M, Farris KB, Stein JD. Patterns of Glaucoma Medication Adherence over Four Years of Follow-Up. Ophthalmology. 2015 Oct;122(10):2010-21. doi: 10.1016/j.ophtha.2015.06.039. Epub 2015 Aug 25.

  PMID: 26319441 BACKGROUND

• Zolnierek KB, Dimatteo MR. Physician communication and patient adherence to treatment: a meta-analysis. Med Care. 2009 Aug;47(8):826-34. doi: 10.1097/MLR.0b013e31819a5acc.

  PMID: 19584762 BACKGROUND

• Newman-Casey PA, Robin AL, Blachley T, Farris K, Heisler M, Resnicow K, Lee PP. The Most Common Barriers to Glaucoma Medication Adherence: A Cross-Sectional Survey. Ophthalmology. 2015 Jul;122(7):1308-16. doi: 10.1016/j.ophtha.2015.03.026. Epub 2015 Apr 24.

  PMID: 25912144 BACKGROUND

MeSH Terms

Conditions

Glaucoma

Interventions

Amyloid

Condition Hierarchy (Ancestors)

Ocular Hypertension; Eye Diseases

Intervention Hierarchy (Ancestors)

Multiprotein Complexes; Macromolecular Substances; Proteins; Amino Acids, Peptides, and Proteins

Study Officials

• Frank Brodie, MD

  UCSF, Department of Ophthalmology

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: SUPPORTIVE CARE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: September 13, 2023
• First Posted: September 21, 2023
• Study Start: September 1, 2024
• Primary Completion: June 1, 2025
• Study Completion: June 1, 2025
• Last Updated: December 30, 2025

Record last verified: 2025-12

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)