NCT06043596

Brief Summary

The goal of this study is to evaluate the impact of SafeSpace Sexual Health App, an innovative sexual health promotion program focused on reducing sexual risk factors and promoting sexual and reproductive health and wellbeing among young people assigned female or intersex at birth, particularly Black and/or Latine youth, LGBTQ+ youth, youth in states with high teen birth rates and youth who live in rural communities. This study utilizes a two-arm randomized control trial design to measure impacts of receiving the SafeSpace Sexual Health program compared to receiving a similar-length control app program, SafeSpace General Health that focuses on general health. The investigators will ask participants to:

  • Keep the SafeSpace app downloaded to their device and visit the app regularly over the course of 10 weeks.
  • Provide contact information.
  • Receive and open app push notifications for 10 weeks (up to 3 per week).
  • Complete 3 online surveys over a year: baseline, short-term follow-up (10 weeks after baseline), and long-term follow up (9 months after short-term follow-up).
  • Receive occasional text messages from the study team.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,000

participants targeted

Target at P75+ for not_applicable

Timeline
5mo left

Started Jun 2023

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress88%
Jun 2023Sep 2026

Study Start

First participant enrolled

June 12, 2023

Completed
3 months until next milestone

First Submitted

Initial submission to the registry

September 12, 2023

Completed
9 days until next milestone

First Posted

Study publicly available on registry

September 21, 2023

Completed
2.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 11, 2026

Completed
7 months until next milestone

Study Completion

Last participant's last visit for all outcomes

September 29, 2026

Expected
Last Updated

November 21, 2023

Status Verified

November 1, 2023

Enrollment Period

2.7 years

First QC Date

September 12, 2023

Last Update Submit

November 17, 2023

Conditions

Outcome Measures

Primary Outcomes (1)

  • Penile-vaginal sex without a condom or a more effective method of contraception

    Yes = Had penile-vaginal sex without using pill, shot, patch, ring, IUD, implant, or condom every time; No = Did not have penile-vaginal sex OR always used pill, shot, patch, ring, IUD, implant, or condom during penile-vaginal sex

    Past 3 months at baseline; past 9 months at long-term follow-up

Secondary Outcomes (4)

  • Penile-vaginal sex or anal sex without a condom every time

    Past 3 months at baseline; past 9 months at long-term follow-up

  • Utilization of sexual health services

    Has received SRH services in the past 12 months or has an appointment scheduled in the next 3 months at baseline; Received SRH services in the past 9 months or has an appointment scheduled in the next 3 months at long-term follow-up.

  • Number of Sexual and Reproductive Health topics discussed with a trusted adult in the past 3 months.

    Past 3 months at baseline; past 10 weeks at short-term follow-up; past 9 months at long-term follow-up

  • Sexual agency during every recent sexual experience or no recent sexual experiences

    Past 3 months at baseline; past 10 weeks at short-term follow-up; past 9 months at long-term follow-up

Study Arms (2)

SafeSpace Sexual Health

EXPERIMENTAL

The proposed intervention is a 10-week app-based program, SafeSpace Sexual Health. SafeSpace Sexual Health will be implemented using a secure, anonymous mobile app that uses authentic stories to engage young people with sexual health information and resources. The program addresses healthy relationships, anatomy and physiology, identity, adolescent development, STIs/HIV, pregnancy and reproduction, decision-making, personal safety, communication, and accessing healthcare. Each lesson includes a story written by youth with lived experience, two to three key facts developed by sexual health experts, a reflection prompt, and two to three reputable resources.

Behavioral: SafeSpace Sexual Health

SafeSpace General Health

ACTIVE COMPARATOR

Participants in the control condition will participate in a 10-week app-based general health program, SafeSpace General Health. Lessons address general health topics including self-care, stress, sleep, nutrition, physical activity, substance use, driving and seatbelt use, and social media. Each lesson contains 2-3 key facts created by public health experts and reputable resources. Similar to SafeSpace Sexual Health, youth will receive SafeSpace General Health over 10 weeks, although SafeSpace General Health includes one lesson per week and does not contain youth stories or reflection prompts.

Behavioral: SafeSpace General Health

Interventions

The overall goal of the program is to prevent adolescent pregnancy and STIs by increasing sexual agency, increasing the use of condoms and contraception, and promoting healthy relationships and healthy life skills among adolescents.

SafeSpace Sexual Health

This arm represents the comparison group. SafeSpace General Health will act as the active comparator, while providing youth with lessons, facts, and resources about general health topics.

SafeSpace General Health

Eligibility Criteria

Age14 Years - 18 Years
Sexfemale
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

  • Participants must be assigned female or intersex at birth
  • Participants must be youth in the U.S. (14-18 years old)
  • Participants must have daily access to an iPhone

You may not qualify if:

  • \- Participants must not be currently pregnant or currently trying to become pregnant
  • Other Criteria:
  • \- The study's priority/preference population is for Black and/or Latine youth, LGBTQ+ youth, youth from geographic areas with high teen birth rates, and youth living in rural areas.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Child Trends

Bethesda, Maryland, 20814, United States

RECRUITING

MeSH Terms

Conditions

Health BehaviorPatient Acceptance of Health CareUnsafe SexSexually Transmitted Diseases

Condition Hierarchy (Ancestors)

BehaviorTreatment Adherence and ComplianceSexual BehaviorCommunicable DiseasesInfectionsGenital DiseasesUrogenital DiseasesDisease AttributesPathologic ProcessesPathological Conditions, Signs and Symptoms

Study Officials

  • Jennifer Manlove, PhD

    Child Trends

    STUDY DIRECTOR
  • Elizabeth L Cook, MSPH

    Child Trends

    STUDY DIRECTOR
  • Riley Steiner, PhD

    Power to Decide

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Elizabeth Cook, MSPH

CONTACT

Jennifer Manlove, PhD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
PARALLEL
Model Details: This research project will use an individual randomized controlled trial design in which youth recruited from social media ads will be randomized 1:1 into the experimental condition (about sexual health) and the control condition (about general health).
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 12, 2023

First Posted

September 21, 2023

Study Start

June 12, 2023

Primary Completion

March 11, 2026

Study Completion (Estimated)

September 29, 2026

Last Updated

November 21, 2023

Record last verified: 2023-11

Data Sharing

IPD Sharing
Will not share

Locations