Point-of-care Ultrasound to Assess Hydronephrosis in Patients With Acute Kidney Injury in the Emergency Department

NCT06040736 | Completed

• 1 other identifier: RECHMPL21_0158
• Study Type: observational
• Target: 155
• Locations: 1 country
• Sites: 1

Brief Summary

Acute kidney injury (AKI) is a common diagnosis in the emergency department (ED), and urinary tract obstruction is a contributing cause that requires rapid diagnosis and therapeutic management. This observational study aims at assessing the accuracy of point-of-care ultrasound (POCUS), performed by the emergency physician (EP) for the detection of dilatation or distension of the kidney secondary to urinary tract obstruction, in emergency department patients presenting with acute kidney injury (AKI). Participants will undergo a bedside POCUS of the urinary tract by the EP followed by central imaging evaluation by a radiologist (either ultrasound or renal computed tomography (CT) or both). Researchers will compare both diagnosis. Study hypothesis is that trained emergency physicians can rapidly and reliably diagnose renal tract obstruction at POCUS in the context of AKI.

Conditions

Acute Kidney Injury; Urinary Tract Obstruction

Keywords

Point-of-care ultrasound; Acute kidney injury; Hydronephrosis; urinary tract obstruction; Emergency Medicine

Outcome Measures

Primary Outcomes (1)

• Performance of pont of care ultrasound (POCUS) for the diagnosis of hydronephrosis

  Performance of POCUS for the detection of hydronephrosis compared to radiology imaging as the gold standard (Sensitivity, Specificity, Negative Predictive Value, Positive Predicted Value)

  1 day (Emergency department (ED) length of stay)

Secondary Outcomes (2)

• Level of agreement between ED Pocus and central radiology imaging for the diagnosis of hydronephrosis

  1 day (ED length of stay)

• Risk Factors for POCUS misdiagnosis

  1 day (ED length of stay)

Study Arms (1)

Patients with acute kidney injury

Emergency department patients presenting with acute kidney injury, regardless of their complaint for ED admission. AKI is defined based on increase in serum creatinine (SCr) levels according to Kdigo criteria Patients will undergo both a bedside point of care ultrasonography and a central radiology imaging evaluation of hydronephrosis as part of routine care

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Patients admitted to the emergency department of Montpellier university hospital

You may qualify if:

• Patient with acute kidney injury defined by changes in serum creatinine (sCr) level between the index sCr at ED admission and pre and/or post sCr controls (Kidney Disease Improving Global Outcome criteria)
• Patient who does not oppose to the use of their data

You may not qualify if:

• Vesical globe
• Polycystic kidney disease
• Known renal tumor
• Horseshoe kidney

Sponsors & Collaborators

• University Hospital, Montpellier: lead

Study Sites (1)

university hospital of Montpellier

Montpellier, France

Location

MeSH Terms

Conditions

Acute Kidney Injury; Hydronephrosis

Condition Hierarchy (Ancestors)

Renal Insufficiency; Kidney Diseases; Urologic Diseases; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Male Urogenital Diseases

Study Officials

• Mustapha SEBBANE, MD, PhD

  University Hospital, Montpellier

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: September 4, 2023
• First Posted: September 18, 2023
• Study Start: July 2, 2020
• Primary Completion: September 30, 2023
• Study Completion: September 30, 2023
• Last Updated: August 29, 2025

Record last verified: 2025-08

Data Sharing

• IPD Sharing: Will not share

Locations

FR (1)