Evaluate Aerobic Exercise on Myocardial Fibrosis and Intestinal Flora in Dilated Cardiomyopathy Diagnosed First Time.

NCT06039969 | Unknown

• 1 other identifier: 20230911
• Study Type: observational
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

To invegstive the Changes of Intestinal Flora and the improvements of Cardiac Fibrosis in Patients With Dilated Cardiomyopathy Diagnosed for the First Time by heart Rehabilitation

Conditions

Cardiac Rehabilitation; Myocardial Fibrosis

Keywords

Aerobic exercise rehabilitation; Myocardial Fibrosis; human gut microbiome; cardiac magnetic resonance

Outcome Measures

Primary Outcomes (1)

• myocardial fibrosis

  Assessment of myocardial fibrosis based on cardiac MRI examination

  first admission six months one year

Secondary Outcomes (1)

• Bacterial spectrum of intestine

  first admission six months one year

Other Outcomes (1)

• cardiac fitiness

  first admission six months one year

Study Arms (1)

Cardiac MRI will be performed in patients with heart failure caused by cardiomyopathy.

Cardiac MRI will be performed in patients with heart failure caused by cardiomyopathy. At the same time Collect patient feces.this is a obvertional study ,ther is no intervetion

Eligibility Criteria

• Age: 18 Years - 70 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

patients who were hospitalized for heart failure for the first time and were finally diagnosed with dilated cardiomyopathy

You may qualify if:

• 、Patients hospitalized for the first time because of heart failure 2、The patient who was definitely diagnosed as dilated cardiomyopathy for the first time

You may not qualify if:

• 、Other types of cardiomyopathy 2、Has been diagnosed as dilated cardiomyopathy. 3、malignant tumor 4、acute infection 5、Cannot perform cardiopulmonary exercise test.

Sponsors & Collaborators

• Nanjing Medical University: lead

Study Sites (1)

Huai'An First People'S Hospital

Huai'an, Jiangsu, 223300, China

RECRUITING

Biospecimen

Retention: SAMPLES WITHOUT DNA

Cardiac MRI data and patient's feces will be collected.Changes in intestinal flora spectrum will be detected.

Study Officials

• XiWen Zhang, MD

  Huai'an First People's Hospital

  STUDY DIRECTOR

Central Study Contacts

Jin Geng, MD

CONTACT

+86-17753124846; gj885258@163.com

XiWen Zhang, MD

CONTACT

Study Design

• Study Type: observational
• Observational Model: CASE CROSSOVER
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: associate doctor

Study Record Dates

• First Submitted: September 11, 2023
• First Posted: September 15, 2023
• Study Start: October 1, 2023
• Primary Completion: October 1, 2024
• Study Completion: October 1, 2025
• Last Updated: September 15, 2023

Record last verified: 2023-09

Data Sharing

• IPD Sharing: Will not share

Locations

CN (1)