The Relationship Between Rheumatoid Arthritis and Osteoporosis and Factors Contributing to This Connection

NCT06038292 | Not Yet Recruiting

• 1 other identifier: RA&OP Relationship
• Study Type: observational
• Target: 105
• Locations: 0 countries
• Sites: N/A

Brief Summary

This study aims to explore the association between RA and osteoporosis and highlight the risk factors that RA patients have that may cause or affect osteoporosis progress.

Conditions

RA & OP Relationship

Outcome Measures

Primary Outcomes (1)

• The percentage of patients with Rheumatoid Arthritis who have Osteoporosis.

  to explore the association between RA and osteoporosis and highlight the risk factors that RA patients have that may cause or affect osteoporosis progress by measuring the percentage of patents with RA who have osteoporosis.

  baseline

Secondary Outcomes (1)

• Correlation between age, disease duration, disease activity, and treatment with osteoporosis

  baseline

Interventions

DXA Scan RADIATION

DEXA (dual x-ray absorptiometry) Scans which measure bone density (thickness and strength of bones) by passing a high and low energy x-ray beam (a form of ionizing radiation) through the body, usually in the hip, the spine and the bones of the hands and can easily diagnose osteoporosis.

Eligibility Criteria

• Age: 18 Years - 75 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patient more than 18 years old classified as rheumatoid arthritis based on ACR/EULAR 2010 Classification criteria * Patients with other clinical conditions that causes secondary osteoporosis as Diabetes Mellitus, renal, liver diseases, thyroid and parathyroid disorder excluded because of probability of these disease to be a reason of osteoporosis.

You may qualify if:

• Patient more than 18 years old classified as rheumatoid arthritis based on ACR/EULAR 2010 Classification criteria.

You may not qualify if:

• Patients with other clinical conditions that causes secondary osteoporosis as Diabetes Mellitus, renal, liver diseases, thyroid and parathyroid disorders.

Sponsors & Collaborators

• Assiut University: lead

Related Links

• Bone mineral density in patients with rheumatoid arthritis: relation between disease severity and low bone mineral density
• IL-26 Is Overexpressed in Rheumatoid Arthritis and Induces Proinflammatory Cytokine Production and Th17 Cell Generation
• Rheumatoid arthritis in adults: management

MeSH Terms

Interventions

Absorptiometry, Photon

Intervention Hierarchy (Ancestors)

Radiography; Diagnostic Imaging; Diagnostic Techniques and Procedures; Diagnosis; Densitometry; Photometry; Chemistry Techniques, Analytical; Investigative Techniques

Central Study Contacts

Felopateer Sedhom, Master

CONTACT

+2 01223929829; felopateertalaat115@gmail.com

Mostafa Haredy, MD

CONTACT

+2 0100 107 9913; Mostafaharedy56@gmail.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: CROSS SECTIONAL
• Target Duration: 8 Months
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: felopateer talaat

Study Record Dates

• First Submitted: September 8, 2023
• First Posted: September 14, 2023
• Study Start: March 1, 2024
• Primary Completion (Estimated): October 1, 2026
• Study Completion (Estimated): November 1, 2026
• Last Updated: February 21, 2024

Record last verified: 2024-02