NCT06036329

Brief Summary

The goal of this multi-site, prospective, randomized, double arm study without blinding is to test the usability of the Whitsundays mask system at home by patients with Obstructive Sleep Apnea. The main questions it aims to answer are:

  • How the Whitsundays masks performs in the home environment
  • What is the subject's first impression of the Whitsundays mask and what is their preference compared to their own mask
  • What is the difference between the subject's objective therapy data when using the Whitsundays mask compared to their own mask
  • Is there wear and tear of the Whitsundays mask and how frequently do the cushions need replacement Participants will be asked to use the Whitsundays mask for 90 days, answer questionnaires about the initial impression of the mask, the performance of the mask, and their preference compared to their own mask. Researchers will compare one group of subjects who will be provided with cushion replacements to another group who will only be provided with cushion replacements upon request to determine the need for cushion replacement, its frequency, and the reasons for cushion replacement during home usage.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
120

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started May 2023

Shorter than P25 for not_applicable

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 31, 2023

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

July 18, 2023

Completed
2 months until next milestone

First Posted

Study publicly available on registry

September 13, 2023

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 6, 2023

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

November 6, 2023

Completed
Last Updated

February 29, 2024

Status Verified

July 1, 2023

Enrollment Period

5 months

First QC Date

July 18, 2023

Last Update Submit

February 27, 2024

Conditions

Outcome Measures

Primary Outcomes (1)

  • 11 point Likert Scale Questionnaire

    • Subjective scores will be collected from subjects on each attribute being assessed (e.g. visual appeal, ease of use, ease of cleaning, seal, comfort, overall performance etc.). Scores will be collected using an 11-point Likert Scale Questionnaire. Minimum value will be zero. Maximum value will be 10. A higher score indicates better outcomes. A score of 10 is considered very favorable, and a score of 0 is very unfavorable.

    90 days

Secondary Outcomes (8)

  • 11 point Likert Scale Questionnaire

    90 days

  • Apnea Hypopnea Index (AHI)

    90 days

  • Compliance

    90 days

  • Leak

    90 days

  • Pressure Differences

    90 days

  • +3 more secondary outcomes

Study Arms (2)

Group A provided with 1 Whitsundays Nasal mask without a spare mask cushion

EXPERIMENTAL

• Provided with 1 Whitsundays Nasal mask without a spare mask cushion (To be provided as requested)

Device: Group A : provided with 1 Whitsundays Nasal mask without a spare mask cushion

Group B provided with 1 Whitsundays Nasal mask with 2 spare mask cushions

EXPERIMENTAL

• Provided with 1 Whitsundays Nasal mask with 2 spare mask cushions

Device: Group B : provided with 1 Whitsundays Nasal mask with 2 spare mask cushions

Interventions

Group A will be provided with 1 Whitsundays Nasal mask without a spare mask cushion (replacement cushions will only be provided when requested)

Group A provided with 1 Whitsundays Nasal mask without a spare mask cushion

Group B will be provided with 1 Whitsundays Nasal mask with 2 spare mask cushions

Group B provided with 1 Whitsundays Nasal mask with 2 spare mask cushions

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patients willing to give written informed consent
  • Patients who can read and comprehend English
  • Patients who ≥ 18 years of age
  • Patients being treated for OSA with a PAP device for ≥ 6 months
  • Patients currently using a ResMed PAP device (S9, AirSense 10 \& AirSense 11) compatible with AirView (with cellular data connectivity and has been sending device data to the cloud)
  • Patients currently using ResMed AirFit N30i or Philips DreamWear™ Nasal
  • Patients who are willing to try the prototype mask for up to 90 nights
  • Patients who are willing to take photos of the prototype mask every 2 weeks for the duration of the study
  • Patients who reside in the USA and intend to stay in the USA for the next 6 months
  • Patients with access to the internet (such as a smartphone or laptop) to complete online surveys

You may not qualify if:

  • Patients using Bilevel flow generators
  • Patients who are or may be pregnant
  • Patients with a preexisting lung disease/condition that would predispose them to pneumothorax (for example: COPD, lung cancer; fibrosis of the lungs; recent (\< 2years) case of pneumonia or lung infection; lung injury.
  • If you are pregnant or planning to become pregnant

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Sleep Data

San Diego, California, 92123, United States

Location

Clayton Sleep Institute

St Louis, Missouri, 63123, United States

Location

MeSH Terms

Conditions

Sleep Apnea, Obstructive

Condition Hierarchy (Ancestors)

Sleep Apnea SyndromesApneaRespiration DisordersRespiratory Tract DiseasesSleep Disorders, IntrinsicDyssomniasSleep Wake DisordersNervous System Diseases

Study Officials

  • William Hevener, RPSGT

    Sleep Data

    PRINCIPAL INVESTIGATOR
  • Matthew Uhles, MS

    Clayton Sleep Institute

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
OTHER
Intervention Model
PARALLEL
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 18, 2023

First Posted

September 13, 2023

Study Start

May 31, 2023

Primary Completion

November 6, 2023

Study Completion

November 6, 2023

Last Updated

February 29, 2024

Record last verified: 2023-07

Data Sharing

IPD Sharing
Will not share

Locations