Expanded Access Protocol of Troriluzole in Patients With Spinocerebellar Ataxia (SCA)

NCT06034886 | Unknown

• 1 other identifier: BHV4157-401
• Study Type: expanded_access
• Target: N/A
• Locations: 0 countries
• Sites: N/A

Brief Summary

The purpose of this expanded access protocol is to provide access to the investigational drug troriluzole in patients with spinocerebellar ataxia (SCA).

Conditions

SCA; Spinocerebellar Ataxias

Interventions

Troriluzole DRUG

BHV-4157 140mg, 200mg or 280mg once daily by mouth.

Also known as: BHV-4157

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Patient has a confirmed diagnosis of Spinocerebellar Ataxia (SCA), defined as either clinical evidence supporting diagnosis OR confirmed genotypic diagnosis.
• Adequate hepatic function.

You may not qualify if:

• Patient is known to have acute or chronic liver disease that is clinically significant in the judgement of the Physician.
• Patient has a history of a clinically significant medical condition that would interfere with the patients ability to comply with the expanded access protocol or would place the patient at increased risk.

Sponsors & Collaborators

• Biohaven Pharmaceuticals, Inc.: lead

MeSH Terms

Conditions

Spinocerebellar Ataxias

Condition Hierarchy (Ancestors)

Cerebellar Ataxia; Cerebellar Diseases; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Spinocerebellar Degenerations; Spinal Cord Diseases; Heredodegenerative Disorders, Nervous System; Neurodegenerative Diseases; Ataxia; Dyskinesias; Neurologic Manifestations; Genetic Diseases, Inborn; Congenital, Hereditary, and Neonatal Diseases and Abnormalities

Central Study Contacts

Early Access Care

CONTACT

1-203-441-7938; Troriluzole.EAP@earlyaccesscare.com

Study Design

• Study Type: expanded access
• Sponsor Type: INDUSTRY
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: September 5, 2023
• First Posted: September 13, 2023
• Last Updated: January 9, 2026

Record last verified: 2026-01