Stone Disease of the Urinary Tract in Children

NCT06032364 | Recruiting

• 1 other identifier: 9020
• Study Type: observational
• Target: 140
• Locations: 1 country
• Sites: 1

Brief Summary

The incidence of stone disease of the urinary tract in children is increasingly increasing with a remarkable economic impact for its management. This incidence is variable according to race, geographic region, socio-economic status and dietary habits. Oxalo-calcium stones are the most common but the biochemical nature of urinary stones varies depending on the region where those of a phosphatic nature are characterized by a higher incidence in Europe. The diagnosis is confirmed by imaging. The unprepared abdomen (ASP) has low diagnostic accuracy. The scanner is the reference tool but remains an irradiating examination. Risk factors for disease recurrence include primarily the presence of an underlying urinary metabolic abnormality and young age. Urinary metabolic abnormalities vary from one study to another. The understanding of lithogenesis, its evaluation as well as the therapeutic options is essential for adequate and adapted management in the pediatric population.

Conditions

Urinary Lithiasis

Keywords

Urinary Lithiasis; Stone disease; Urolithiasis; Urinary Calculi

Outcome Measures

Primary Outcomes (1)

• Study of the modalities of the therapeutic management of children with urinary stones, retrospective description of the evolutionary aspects and the risk factors associated with recurrence.

  This study is retrospective on already existing data

  Files analysed retrospectively from January 01, 2010 to December 31, 2022 will be examined

Eligibility Criteria

• Age: 1 Year - 17 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17)
• Sampling Method: Non-Probability Sample

Study Population

Patients aged less than 18 years presenting with lithiasis of the urinary tree in one of the two departments concerned between 01/01/2010 and 12/31/2022

You may qualify if:

• Patients aged less than 18 years.
• Both sexes.
• Subjects presenting with lithiasis of the urinary tree in one of the two departments concerned between 01/01/2010 and 12/31/2022
• Subject not opposing, after information, the reuse of their data for the purposes of this research.
• Holders of parental authority who do not object, after being informed, to the reuse of their child's data for the purposes of this research.

You may not qualify if:

• Subject or holder of parental authority having expressed opposition to participating in the study.
• Non-usable patient files: insufficient data.

Sponsors & Collaborators

• University Hospital, Strasbourg, France: lead

Study Sites (1)

Service de Pédiatrie 1 - CHU de Strasbourg - France

Strasbourg, 67091, France

RECRUITING

MeSH Terms

Conditions

Urolithiasis; Urinary Calculi

Condition Hierarchy (Ancestors)

Urologic Diseases; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Male Urogenital Diseases; Calculi; Pathological Conditions, Anatomical; Pathological Conditions, Signs and Symptoms

Central Study Contacts

Isabelle TALON, MD

CONTACT

33 3 88 12 72 96; Isabelle.TALON@chru-strasbourg.fr

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: August 31, 2023
• First Posted: September 13, 2023
• Study Start: August 23, 2023
• Primary Completion: June 23, 2025
• Study Completion: June 23, 2025
• Last Updated: November 5, 2024

Record last verified: 2024-11

Locations

FR (1)