Insecure Attachment and Psychosocial Functioning in Autistic Adults Are Mediated by Depression and Paranoid Ideation

NCT06030167 | Completed

• 1 other identifier: CWO-27-004
• Study Type: interventional
• Target: 83
• Locations: 1 country
• Sites: 1

Brief Summary

The present study examines if depressive symptoms, paranoid ideation, and emotion regulation strategies mediate the relationship between attachment and psychosocial functioning in autistic adults.

Conditions

Autism Spectrum Disorder

Keywords

Autism; Attachment; Psychosocial functioning; Adults

Outcome Measures

Primary Outcomes (2)

• Experiences in Close Relationships - Revised questionnaire (ECR-r)

  Measuring self-rated levels of insecure attachment in 83 adults with autism spectrum disorder. Welch's two sample t-test was used to compare the ECR-r data between the participants and (non-)clinical controls drawn from the manuals of the used measure. The ECR-R is a 36-item measure designed to assess individual differences with respect to attachment-related anxiety (i.e., the extent to which people are insecure versus secure about the availability and responsiveness of romantic partners; items 1 to 18) and attachment-related avoidance (i.e., the extent to which people are uncomfortable being close to others versus secure depending on others; items 19 to 36). The items are scored on a 7-point scale, with higher scores (\>= 4) indicating more insecure attachment. A mean score (ranging from 0 to 7) is calculated for both attachment styles.

  15 minutes

• World Health Organisation Disability Assessment Schedule 2.0 (WHODAS 2.0)

  Measuring self-rated levels of psycho-social functioning in 83 autistic adults. Welch's two sample t-test was used to compare the WHODAS 2.0 data between the participants and (non-)clinical controls drawn from the manuals of the used measure. WHODAS 2.0 is a generic assessment self-report for health and disability in adults, consisting of 36 items on a 5-point scale (none, mild, moderate, severe, and extreme) covering six domains: cognitions, mobility, self-care, interaction, life activities, and participation in society. WHODAS 2.0 asks the individual to rate how much difficulty they have had in specific areas of functioning during the past 30 days. WHODAS 2.0 produces standardized disability levels and profiles by summing six domain scores and converting the summary score into a metric range from 0 (= no disability) to 100 (= full disability).

  15 minutes

Secondary Outcomes (3)

• Beck Depression Inventory-Second Edition-Dutch version-Revised (BDI-2-NL-R)

  10 minutes

• Green Paranoid Thought Scales (GPTS)

  15 minutes

• FEEL-E Questionnaire for Emotion Regulation in Adults (FEEL-E)

  20 minutes

Study Arms (1)

Assessment of attachment and psychosocial functioning in adults with ASD

OTHER

Questionaires about attachment, psychosocial functioning, depressive symptoms, paranoid ideation, and emotion regulation were administered to 83 autistic adults (50 males, 33 females).

Behavioral: Insecure attachment and psychosocial functioning in autistic adults

Interventions

Insecure attachment and psychosocial functioning in autistic adults BEHAVIORAL

Questionaires about attachment, psychosocial functioning, depressive symptoms, paranoid ideation, and emotion regulation were administered to 83 autistic adults (50 males, 33 females).

Assessment of attachment and psychosocial functioning in adults with ASD

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• a primary clinical diagnosis of DSM-5 ASD (APA, 2013)
• age ≥ 18 years
• at least eight years of education.

You may not qualify if:

• intellectual disability (IQ ≤ 80)
• presence of current suicidal ideation.

Sponsors & Collaborators

• Parnassia Groep: lead

Study Sites (1)

Parnassia Antes

Rotterdam, South Holland, 3083AK, Netherlands

Location

MeSH Terms

Conditions

Autism Spectrum Disorder; Autistic Disorder

Interventions

Psychosocial Functioning

Condition Hierarchy (Ancestors)

Child Development Disorders, Pervasive; Neurodevelopmental Disorders; Mental Disorders

Intervention Hierarchy (Ancestors)

Psychology, Developmental; Psychology; Behavioral Sciences; Behavioral Disciplines and Activities; Health Status; Demography; Epidemiologic Measurements; Public Health; Environment and Public Health

Study Officials

• Richard Vuijk, Dr.

  Parnassia Antes

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: DIAGNOSTIC
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: July 26, 2023
• First Posted: September 8, 2023
• Study Start: October 1, 2017
• Primary Completion: June 30, 2019
• Study Completion: June 30, 2019
• Last Updated: September 8, 2023

Record last verified: 2023-09

Data Sharing

• IPD Sharing: Will not share

Locations

NL (1)