NCT06028854

Brief Summary

After surgical tissue damage, cellular blood components are involved in tissue repair processes, yet their preoperative characteristics are not considered in routine clinical practice.

Trial Health

53
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial recruitment is currently suspended
Enrollment
40

participants targeted

Target at P25-P50 for all trials

Timeline
19mo left

Started Oct 2025

Typical duration for all trials

Geographic Reach
1 country

2 active sites

Status
suspended

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress26%
Oct 2025Dec 2027

First Submitted

Initial submission to the registry

August 31, 2023

Completed
8 days until next milestone

First Posted

Study publicly available on registry

September 8, 2023

Completed
2.1 years until next milestone

Study Start

First participant enrolled

October 15, 2025

Completed
2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 15, 2027

Expected
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 15, 2027

Last Updated

December 30, 2024

Status Verified

December 1, 2024

Enrollment Period

2 years

First QC Date

August 31, 2023

Last Update Submit

December 26, 2024

Conditions

Surgical Wound

Outcome Measures

Primary Outcomes (1)

  • Death

    The number of deceased patients.

    1 year

Study Arms (2)

High Neutrophil count

Patients with high neutrophil count in their preoperative complete blood count

Low Neutrophil count

Patients with low neutrophil count in their preoperative complete blood count

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients with acute intrabdominal pathology who requires surgery in the next 24 hours.

You may qualify if:

  • Patients between 18 and 65 years of age at surgery.
  • Patients with acute intra-abdominal pathology requiring emergency surgery.
  • A complete blood count was performed in the emergency department of our center within 24 hours before surgery.

You may not qualify if:

  • Patients who are users of anticoagulation before admission for any reason
  • Patients who have had previous hospitalization or surgery in the last 6 months.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Hospital Clínico de la Universidad de Chile

Independencia, Santiago Metropolitan, 8380456, Chile

Location

Hospital Clínico Universidad de Chile

Santiago, Santiago Metropolitan, 8380456, Chile

Location

Biospecimen

Retention: SAMPLES WITH DNA

Blood cells

MeSH Terms

Conditions

Surgical Wound

Condition Hierarchy (Ancestors)

Wounds and Injuries

Study Officials

  • Felipe Maldonado

    Hospital Clinico de la Universidad de Chile

    STUDY CHAIR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 31, 2023

First Posted

September 8, 2023

Study Start

October 15, 2025

Primary Completion (Estimated)

October 15, 2027

Study Completion (Estimated)

December 15, 2027

Last Updated

December 30, 2024

Record last verified: 2024-12

Data Sharing

IPD Sharing
Will not share

Locations

CL(2)