NCT06021886

Brief Summary

CS scar impact on ART outcomes, Retrospective Cohort Study IVF outcome can be affected by the presence of caesarean section scar with or without defect in different ways

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
510

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jun 2023

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 15, 2023

Completed
6 days until next milestone

First Submitted

Initial submission to the registry

June 21, 2023

Completed
2 months until next milestone

First Posted

Study publicly available on registry

September 1, 2023

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2024

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2024

Completed
Last Updated

November 21, 2023

Status Verified

November 1, 2023

Enrollment Period

7 months

First QC Date

June 21, 2023

Last Update Submit

November 20, 2023

Conditions

Fertility Issues

Keywords

CS Scar Impact on ART Outcomes

Outcome Measures

Primary Outcomes (1)

  • CS scar impact on ART outcomes, Retrospective Cohort Study

    Clinical pregnancy rate

    2015 to 2022,

Secondary Outcomes (1)

  • ART outcomes

    2015 to 2022,

Study Arms (3)

patient without scar

history of euploid embryo transfer

patient with cs scar no Niche

history of euploid embryo transfer

patient with cs scar with niche

history of euploid embryo transfer

Eligibility Criteria

Age25 Years - 40 Years
Sexfemale(Gender-based eligibility)
Healthy VolunteersNo
Age GroupsAdult (18-64)
Sampling MethodProbability Sample
Study Population

All women who underwent an embryo transfer with a Euploid embryo between 2005 and 2022, who meet the inclusion criteria will be included in the study. To compare the success rates and outcomes of pregnancies of frozen embryo transfer for euploid embryos in patients without caesarean section, and who had caesarean section (with or without a NICHE) after euploid embryo transfer.

You may qualify if:

  • Age 25-40 years old.
  • Euploid embryo transfer.
  • Medically free
  • BMI less tha 30 kg/m2
  • Hormone therapy preparation for FET.

You may not qualify if:

  • Previous uterine scar other than cesarean section.
  • Congenital uterine abnormalities
  • Presence of intrauterine lesions e.g., polyp, fibroid,
  • Endometriosis or adenomyosis
  • Hydrosalpinx, Chronic endometritis

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

HealthPlus fertility Centre

Abu Dhabi, United Arab Emirates

RECRUITING

MeSH Terms

Conditions

Infertility

Condition Hierarchy (Ancestors)

Genital DiseasesUrogenital Diseases

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Reproductive medicine consultant

Study Record Dates

First Submitted

June 21, 2023

First Posted

September 1, 2023

Study Start

June 15, 2023

Primary Completion

January 1, 2024

Study Completion

January 1, 2024

Last Updated

November 21, 2023

Record last verified: 2023-11

Locations

AE(1)